Candida albicans FRE8 encodes a member of the NADPH oxidase family that produces a burst of ROS during fungal morphogenesis.

Candida albicans FRE8 encodes a member of the NADPH oxidase family that produces a burst of ROS during fungal morphogenesis.

Until recently, NADPH oxidase (NOX) enzymes were thought to be a property of multicellularity, where the reactive oxygen species (ROS) produced by NOX acts in signaling processes or in attacking invading microbes through oxidative damage. We demonstrate here that the unicellular yeast and opportunis...

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Bibliographic Details
Main Authors: Diego C P Rossi, Julie E Gleason, Hiram Sanchez, Sabrina S Schatzman, Edward M Culbertson, Chad J Johnson, Christopher A McNees, Carolina Coelho, Jeniel E Nett, David R Andes, Brendan P Cormack, Valeria C Culotta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1006763

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