STING pathway contributes to the prognosis of hepatocellular carcinoma and identification of prognostic gene signatures correlated to tumor microenvironment

STING pathway contributes to the prognosis of hepatocellular carcinoma and identification of prognostic gene signatures correlated to tumor microenvironment

Abstract Background Hepatocellular carcinoma (HCC) is one of the most malignant solid tumors worldwide. Recent evidence shows that the stimulator of interferon genes (STING) pathway is essential for anti-tumor immunity via inducing the production of downstream inflammatory cytokines. However, its im...

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Bibliographic Details
Main Authors: Zhangya Pu, Jinghua Liu, Zelong Liu, Fang Peng, Yuanyuan Zhu, Xiaofang Wang, Jiayan He, Panpan Yi, Xingwang Hu, Xuegong Fan, Jiang Chen
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Cancer Cell International
Subjects:
Hepatocellular carcinoma
Nomogram model
Prognostic gene signature
Immune cell infiltrates
Tumor microenvironment
Immune checkpoints
Online Access:https://doi.org/10.1186/s12935-022-02734-4

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