Factors That Control the Force Needed to Unfold a Membrane Protein in Silico Depend on the Mode of Denaturation

Factors That Control the Force Needed to Unfold a Membrane Protein in Silico Depend on the Mode of Denaturation

Single-molecule force spectroscopy methods, such as AFM and magnetic tweezers, have proved extremely beneficial in elucidating folding pathways for soluble and membrane proteins. To identify factors that determine the force rupture levels in force-induced membrane protein unfolding, we applied our n...

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Bibliographic Details
Main Authors: Nabil F. Faruk, Xiangda Peng, Tobin R. Sosnick
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
AFM
magnetic tweezers
simulation
unfolded
denatured
SMFS
Online Access:https://www.mdpi.com/1422-0067/24/3/2654

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