A zebrafish transgenic model of Ewing’s sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis
SUMMARY Ewing’s sarcoma, a malignant bone tumor of children and young adults, is a member of the small-round-blue-cell tumor family. Ewing’s sarcoma family tumors (ESFTs), which include peripheral primitive neuroectodermal tumors (PNETs), are characterized by chromosomal translocations that generate...
Main Authors: | Stefanie W. Leacock, Audrey N. Basse, Garvin L. Chandler, Anne M. Kirk, Dinesh Rakheja, James F. Amatruda |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2012-01-01
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Series: | Disease Models & Mechanisms |
Online Access: | http://dmm.biologists.org/content/5/1/95 |
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