Optimizing androgen receptor prioritization using high-throughput assay-based activity models

Optimizing androgen receptor prioritization using high-throughput assay-based activity models

Introduction: Computational models using data from high-throughput screening assays have promise for prioritizing and screening chemicals for testing under the U.S. Environmental Protection Agency’s Endocrine Disruptor Screening Program (EDSP). The purpose of this work was to demonstrate a data proc...

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Bibliographic Details
Main Authors: Ronnie Joe Bever, Stephen W. Edwards, Todor Antonijevic, Mark D. Nelms, Caroline Ring, Danni Harris, Scott G. Lynn, David Williams, Grace Chappell, Rebecca Boyles, Susan Borghoff, Kristan J. Markey
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Toxicology
Subjects:
endocrine disruption
androgen receptor
computational toxicology
highthroughput screening
tiered testing
Online Access:https://www.frontiersin.org/articles/10.3389/ftox.2024.1347364/full

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