<i>Usp18</i> Expression in CD169<sup>+</sup> Macrophages is Important for Strong Immune Response after Vaccination with VSV-EBOV

<i>Usp18</i> Expression in CD169<sup>+</sup> Macrophages is Important for Strong Immune Response after Vaccination with VSV-EBOV

Ebola virus epidemics can be effectively limited by the VSV-EBOV vaccine (Ervebo) due to its rapid protection abilities; however, side effects prevent the broad use of VSV-EBOV as vaccine. Mechanisms explaining the efficient immune activation after single injection with the VSV-EBOV vaccine remain m...

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Bibliographic Details
Main Authors: Sarah-Kim Friedrich, Rosa Schmitz, Michael Bergerhausen, Judith Lang, Lamin B. Cham, Vikas Duhan, Dieter Häussinger, Cornelia Hardt, Marylyn Addo, Marco Prinz, Kenichi Asano, Philipp Alexander Lang, Karl Sebastian Lang
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Vaccines
Subjects:
enforced replication
vaccination
innate immunity
adaptive immunity
cd169<sup>+</sup> macrophages
<i>usp18</i>
ebola virus
vsv-ebov
ervebo
Online Access:https://www.mdpi.com/2076-393X/8/1/142

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