Identification of Substituted Amino Acid Hydrazides as Novel Anti-Tubercular Agents, Using a Scaffold Hopping Approach

Identification of Substituted Amino Acid Hydrazides as Novel Anti-Tubercular Agents, Using a Scaffold Hopping Approach

Discovery and development of new therapeutic options for the treatment of <i>Mycobacterium tuberculosis</i> (<i>Mtb</i>) infection, particularly drug-resistant strains, are urgently required to tackle the global burden of this disease. Herein, we reported the synthesis of a n...

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Bibliographic Details
Main Authors: Alistair K. Brown, Ahmed K. B. Aljohani, Fatimah M. A. Alsalem, Joseph L. Broadhead, Jason H. Gill, Yucheng Lu, Jonathan D. Sellars
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Molecules
Subjects:
antibacterial
<i>Mycobacterium tuberculosis</i>
amino acid
hydrazide
Q203
Naphthalene
Online Access:https://www.mdpi.com/1420-3049/25/10/2387

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