Evaluation of genetic risk score models in the presence of interaction and linkage disequilibrium

Evaluation of genetic risk score models in the presence of interaction and linkage disequilibrium

In the area of genetic epidemiology, genetic risk predictive modeling is becoming an important area of translational success. As an increasing number of genetic variants are successfully discovered, the use of multiple genetic variants in constructing a genetic risk score (GRS) for modeling has bee...

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Bibliographic Details
Main Authors:	Ronglin eChe, Alison eMotsinger-Reif
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2013-07-01
Series:	Frontiers in Genetics
Subjects:	Linkage Disequilibrium Correlation association studies d simulation study genetic risk scores
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00138/full

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