Cytologic diagnosis of acinic cell carcinoma of minor salivary gland: a distinct rarely described entity

A rare case of acinic cell carcinoma of minor salivary gland with cervical lymph node metastasis in a 50-year-old man is reported and the literature regarding this type of tumor is reviewed. These tumors arise from either an intercalated duct stem cell or the reserve cell of the salivary gland termi...

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Main Authors: Rana Sherwani, Kafil Akhtar, Murad Ahmad, Abrar Hasan
Format: Article
Language:English
Published: MDPI AG 2011-08-01
Series:Clinics and Practice
Subjects:
Online Access:https://www.clinicsandpractice.org/index.php/cp/article/view/109
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author Rana Sherwani
Kafil Akhtar
Murad Ahmad
Abrar Hasan
author_facet Rana Sherwani
Kafil Akhtar
Murad Ahmad
Abrar Hasan
author_sort Rana Sherwani
collection DOAJ
description A rare case of acinic cell carcinoma of minor salivary gland with cervical lymph node metastasis in a 50-year-old man is reported and the literature regarding this type of tumor is reviewed. These tumors arise from either an intercalated duct stem cell or the reserve cell of the salivary gland terminal tubule but not from both simultaneously. Rarely these neoplasms arise from more mature acinar cells. It is clear that these tumors behave ominously. The 25 year determinate survival rate is 50%, with a 20% incidence of metastasis. Surgical excision is the treatment of choice. Radiotherapy, especially neutron therapy, has a place in the treatment of this tumor but the role of chemotherapy is not exactly known at this time.
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spelling doaj.art-6f62b5d22dcf4d26b7fa6a99f763f0232022-12-22T02:19:08ZengMDPI AGClinics and Practice2039-72752039-72832011-08-011310.4081/cp.2011.e5860Cytologic diagnosis of acinic cell carcinoma of minor salivary gland: a distinct rarely described entityRana Sherwani0Kafil Akhtar1Murad Ahmad2Abrar Hasan3Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh(U.P)Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh(U.P)Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh(U.P)Department of Ear, Nose & Throat (ENT), Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh(U.P)A rare case of acinic cell carcinoma of minor salivary gland with cervical lymph node metastasis in a 50-year-old man is reported and the literature regarding this type of tumor is reviewed. These tumors arise from either an intercalated duct stem cell or the reserve cell of the salivary gland terminal tubule but not from both simultaneously. Rarely these neoplasms arise from more mature acinar cells. It is clear that these tumors behave ominously. The 25 year determinate survival rate is 50%, with a 20% incidence of metastasis. Surgical excision is the treatment of choice. Radiotherapy, especially neutron therapy, has a place in the treatment of this tumor but the role of chemotherapy is not exactly known at this time.https://www.clinicsandpractice.org/index.php/cp/article/view/109minor salivary glandacinic cell carcinomaFNA cytology.
spellingShingle Rana Sherwani
Kafil Akhtar
Murad Ahmad
Abrar Hasan
Cytologic diagnosis of acinic cell carcinoma of minor salivary gland: a distinct rarely described entity
Clinics and Practice
minor salivary gland
acinic cell carcinoma
FNA cytology.
title Cytologic diagnosis of acinic cell carcinoma of minor salivary gland: a distinct rarely described entity
title_full Cytologic diagnosis of acinic cell carcinoma of minor salivary gland: a distinct rarely described entity
title_fullStr Cytologic diagnosis of acinic cell carcinoma of minor salivary gland: a distinct rarely described entity
title_full_unstemmed Cytologic diagnosis of acinic cell carcinoma of minor salivary gland: a distinct rarely described entity
title_short Cytologic diagnosis of acinic cell carcinoma of minor salivary gland: a distinct rarely described entity
title_sort cytologic diagnosis of acinic cell carcinoma of minor salivary gland a distinct rarely described entity
topic minor salivary gland
acinic cell carcinoma
FNA cytology.
url https://www.clinicsandpractice.org/index.php/cp/article/view/109
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AT muradahmad cytologicdiagnosisofaciniccellcarcinomaofminorsalivaryglandadistinctrarelydescribedentity
AT abrarhasan cytologicdiagnosisofaciniccellcarcinomaofminorsalivaryglandadistinctrarelydescribedentity