Construction of a Rough Surface with Submicron Ti<sub>2</sub>Cu Particle on Ti-Cu Alloy and Its Effect on the Antibacterial Properties and Cell Biocompatibility
Titanium-copper (Ti-Cu) alloy is an advanced antibacterial material with excellent mechanical properties, thermodynamic stability, corrosion resistance and biocompatibility. Sandblasting and acid-etching was applied to the Ti-3Cu alloy to construct a rough surface with Ti<sub>2</sub>Cu p...
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MDPI AG
2022-06-01
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| Series: | Metals |
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| Online Access: | https://www.mdpi.com/2075-4701/12/6/1008 |
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| author | Yanchun Xie Ming Lu Shenshen Cui Hailong Yu Ling Wang Hongdan Ke Erlin Zhang |
| author_facet | Yanchun Xie Ming Lu Shenshen Cui Hailong Yu Ling Wang Hongdan Ke Erlin Zhang |
| author_sort | Yanchun Xie |
| collection | DOAJ |
| description | Titanium-copper (Ti-Cu) alloy is an advanced antibacterial material with excellent mechanical properties, thermodynamic stability, corrosion resistance and biocompatibility. Sandblasting and acid-etching was applied to the Ti-3Cu alloy to construct a rough surface with Ti<sub>2</sub>Cu phase on the surface in order to improve the antibacterial properties and the osseointegration. The phase constitutes and the physical properties were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and confocal laser scanning microscope (CLSM), and the surface chemical properties were analyzed by X-ray photoelectron spectroscopy (XPS) and electrochemical testing. The antibacterial property was assessed by the plate-count method and the cell compatibility was evaluated by the CCK-8 test in order to reveal the effect of surface characteristics on the antibacterial ability and bioactivity. The results demonstrated a rough and lamellar surface structure with many submicron Ti<sub>2</sub>Cu particles on the surface of Ti-3Cu, which could enhance the antibacterial ability and promote the cell proliferation and the initial adhesion of osteoblasts. However, the surface treatment also reduced the corrosion resistance and accelerated the Cu ion release. |
| first_indexed | 2024-03-09T23:02:59Z |
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| id | doaj.art-6f66c351e10a444fab1f47acc6a42c61 |
| institution | Directory Open Access Journal |
| issn | 2075-4701 |
| language | English |
| last_indexed | 2024-03-09T23:02:59Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
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| series | Metals |
| spelling | doaj.art-6f66c351e10a444fab1f47acc6a42c612023-11-23T17:58:45ZengMDPI AGMetals2075-47012022-06-01126100810.3390/met12061008Construction of a Rough Surface with Submicron Ti<sub>2</sub>Cu Particle on Ti-Cu Alloy and Its Effect on the Antibacterial Properties and Cell BiocompatibilityYanchun Xie0Ming Lu1Shenshen Cui2Hailong Yu3Ling Wang4Hongdan Ke5Erlin Zhang6Northern Theater General Hospital, Shenyang 110016, ChinaKey Laboratory for Anisotropy and Texture of Materials, School of Materials Science and Engineering, Education Ministry of China, Northeastern University, Shenyang 110819, ChinaKey Laboratory for Anisotropy and Texture of Materials, School of Materials Science and Engineering, Education Ministry of China, Northeastern University, Shenyang 110819, ChinaNorthern Theater General Hospital, Shenyang 110016, ChinaNorthern Theater General Hospital, Shenyang 110016, ChinaNorthern Theater General Hospital, Shenyang 110016, ChinaKey Laboratory for Anisotropy and Texture of Materials, School of Materials Science and Engineering, Education Ministry of China, Northeastern University, Shenyang 110819, ChinaTitanium-copper (Ti-Cu) alloy is an advanced antibacterial material with excellent mechanical properties, thermodynamic stability, corrosion resistance and biocompatibility. Sandblasting and acid-etching was applied to the Ti-3Cu alloy to construct a rough surface with Ti<sub>2</sub>Cu phase on the surface in order to improve the antibacterial properties and the osseointegration. The phase constitutes and the physical properties were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and confocal laser scanning microscope (CLSM), and the surface chemical properties were analyzed by X-ray photoelectron spectroscopy (XPS) and electrochemical testing. The antibacterial property was assessed by the plate-count method and the cell compatibility was evaluated by the CCK-8 test in order to reveal the effect of surface characteristics on the antibacterial ability and bioactivity. The results demonstrated a rough and lamellar surface structure with many submicron Ti<sub>2</sub>Cu particles on the surface of Ti-3Cu, which could enhance the antibacterial ability and promote the cell proliferation and the initial adhesion of osteoblasts. However, the surface treatment also reduced the corrosion resistance and accelerated the Cu ion release.https://www.mdpi.com/2075-4701/12/6/1008titanium-copper alloysandblasting and etchingantibacterial titanium alloybiocompatibility |
| spellingShingle | Yanchun Xie Ming Lu Shenshen Cui Hailong Yu Ling Wang Hongdan Ke Erlin Zhang Construction of a Rough Surface with Submicron Ti<sub>2</sub>Cu Particle on Ti-Cu Alloy and Its Effect on the Antibacterial Properties and Cell Biocompatibility Metals titanium-copper alloy sandblasting and etching antibacterial titanium alloy biocompatibility |
| title | Construction of a Rough Surface with Submicron Ti<sub>2</sub>Cu Particle on Ti-Cu Alloy and Its Effect on the Antibacterial Properties and Cell Biocompatibility |
| title_full | Construction of a Rough Surface with Submicron Ti<sub>2</sub>Cu Particle on Ti-Cu Alloy and Its Effect on the Antibacterial Properties and Cell Biocompatibility |
| title_fullStr | Construction of a Rough Surface with Submicron Ti<sub>2</sub>Cu Particle on Ti-Cu Alloy and Its Effect on the Antibacterial Properties and Cell Biocompatibility |
| title_full_unstemmed | Construction of a Rough Surface with Submicron Ti<sub>2</sub>Cu Particle on Ti-Cu Alloy and Its Effect on the Antibacterial Properties and Cell Biocompatibility |
| title_short | Construction of a Rough Surface with Submicron Ti<sub>2</sub>Cu Particle on Ti-Cu Alloy and Its Effect on the Antibacterial Properties and Cell Biocompatibility |
| title_sort | construction of a rough surface with submicron ti sub 2 sub cu particle on ti cu alloy and its effect on the antibacterial properties and cell biocompatibility |
| topic | titanium-copper alloy sandblasting and etching antibacterial titanium alloy biocompatibility |
| url | https://www.mdpi.com/2075-4701/12/6/1008 |
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