Inferring repeat-protein energetics from evolutionary information.
Natural protein sequences contain a record of their history. A common constraint in a given protein family is the ability to fold to specific structures, and it has been shown possible to infer the main native ensemble by analyzing covariations in extant sequences. Still, many natural proteins that...
Main Authors: | Rocío Espada, R Gonzalo Parra, Thierry Mora, Aleksandra M Walczak, Diego U Ferreiro |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-06-01
|
Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC5491312?pdf=render |
Similar Items
-
Structural and Energetic Characterization of the Ankyrin Repeat Protein Family.
by: R Gonzalo Parra, et al.
Published: (2015-12-01) -
Resolving the fine structure in the energy landscapes of repeat proteins
by: Murilo N. Sanches, et al.
Published: (2022-01-01) -
Local energetic frustration conservation in protein families and superfamilies
by: Maria I. Freiberger, et al.
Published: (2023-12-01) -
Evolutionary trend of SARS-CoV-2 inferred by the homopolymeric nucleotide repeats
by: Yin Changchuan
Published: (2022-07-01) -
Generalized Glauber Dynamics for Inference in Biology
by: Xiaowen Chen, et al.
Published: (2023-12-01)