Severe Scabies: A French Multi-centre Study Involving 95 Patients with Crusted and Profuse Disease and Review of the Literature
The aim of this multi-centre French retrospective study was to identify severe, i.e. crusted and profuse, scabies patients. Records were retrieved from 22 Dermatology or Infectious Diseases departments in the Ile-de-France from January 2009 to January 2015 to characterize epidemiology, demography, d...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Medical Journals Sweden
2023-03-01
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| Series: | Acta Dermato-Venereologica |
| Subjects: | |
| Online Access: | https://medicaljournalssweden.se/actadv/article/view/5351 |
| _version_ | 1811161294307328000 |
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| author | Charbel Skayem Askour Majda Charlotte Gary Francois Hemery Emmanuel Mahé Frederic Caux Nicolas Dupin Patricia Senet Alix Greder-Belan Brigitte Hillion Cecile Meni Philippe Saiag Guillaume Bellaud Alexandre Bleibtreu Sylvie Lariven Diane Bollens Vincent Descamps Jean-Michel Molina Olivier Bouchaud Daniel Vittecoq Gia Do-Pham Francoise Foulet Francoise Botterel Olivier Chosidow Charlotte Bernigaud |
| author_facet | Charbel Skayem Askour Majda Charlotte Gary Francois Hemery Emmanuel Mahé Frederic Caux Nicolas Dupin Patricia Senet Alix Greder-Belan Brigitte Hillion Cecile Meni Philippe Saiag Guillaume Bellaud Alexandre Bleibtreu Sylvie Lariven Diane Bollens Vincent Descamps Jean-Michel Molina Olivier Bouchaud Daniel Vittecoq Gia Do-Pham Francoise Foulet Francoise Botterel Olivier Chosidow Charlotte Bernigaud |
| author_sort | Charbel Skayem |
| collection | DOAJ |
| description | The aim of this multi-centre French retrospective study was to identify severe, i.e. crusted and profuse, scabies patients. Records were retrieved from 22 Dermatology or Infectious Diseases departments in the Ile-de-France from January 2009 to January 2015 to characterize epidemiology, demography, diagnosis, contributing factors, treatment features, and outcomes in severe scabies. A total of 95 inpatients (57 crusted and 38 profuse) were included. A higher number of cases was observed among elderly patients (>75 years), mostly living in institutions. Thirteen patients (13.6%) reported a history of previously treated scabies. Sixty-three patients (66.3%) had been seen by a previous practitioner for the current episode (up to 8 previous visits). Initial misdiagnosis (e.g. eczema, prurigo, drug-related eruptions, psoriasis) was documented in 41 patients (43.1%). Fifty-eight patients (61%) had already received 1 or more previous treatments for their current episode. Forty percent received corticosteroids or acitretin for an initial diagnosis of eczema or psoriasis. Median time from the onset of symptoms to the diagnosis of severe scabies was 3 months (range 0.3–22). Itch was present in all patients at diagnosis. Most patients (n=84, 88.4%) had comorbidities. Diagnostic and therapeutic approaches varied. Complications occurred in 11.5% of cases. To date, there is no consensus for diagnosis and treatment, and future standardization of is required for optimal management.
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| first_indexed | 2024-04-10T06:12:54Z |
| format | Article |
| id | doaj.art-6f6b79f6b6a342ce98078d6bb2870972 |
| institution | Directory Open Access Journal |
| issn | 0001-5555 1651-2057 |
| language | English |
| last_indexed | 2024-04-10T06:12:54Z |
| publishDate | 2023-03-01 |
| publisher | Medical Journals Sweden |
| record_format | Article |
| series | Acta Dermato-Venereologica |
| spelling | doaj.art-6f6b79f6b6a342ce98078d6bb28709722023-03-02T11:56:49ZengMedical Journals SwedenActa Dermato-Venereologica0001-55551651-20572023-03-0110310.2340/actadv.v103.5351Severe Scabies: A French Multi-centre Study Involving 95 Patients with Crusted and Profuse Disease and Review of the LiteratureCharbel Skayem0Askour Majda1Charlotte Gary2Francois Hemery3Emmanuel Mahé4Frederic Caux5Nicolas Dupin6Patricia Senet7Alix Greder-Belan8Brigitte Hillion9Cecile Meni10Philippe Saiag11Guillaume Bellaud12Alexandre Bleibtreu13Sylvie Lariven14Diane Bollens15Vincent Descamps16Jean-Michel Molina17Olivier Bouchaud18Daniel Vittecoq19Gia Do-Pham20Francoise Foulet21Francoise Botterel22Olivier Chosidow23Charlotte Bernigaud24Dermatology Department, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Henri-Mondor, Créteil, FranceDermatology Department, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Henri-Mondor, Créteil, FranceDermatology Department, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Henri-Mondor, Créteil, FranceService d’Information Médicale, DSIGHM, APHP, Hôpital Henri-Mondor, Créteil, FranceDermatology Department, Centre Hospitalier Victor Dupouy, Argenteuil, FranceDermatology Department, APHP, Hôpital Avicenne, Bobigny, FranceDermatology Department, APHP, Hôpital Cochin, Pavillon Tarnier, Paris, FranceDermatology Department, APHP, Hôpital Tenon, Sorbonne Université, Paris, FranceService de Médecine Interne et Unité de Maladies Infectieuses et Tropicales, Centre Hospitalier de Versailles, Hôpital Mignot, Le Chesnay, FranceDermatology Department, Centre Hospitalier Marne la Vallée, Jossigny, FranceDermatology Department, APHP, Hôpital Necker-Enfants malades, Paris, FranceDermatology Department, APHP, Hôpital Ambroise Paré, Boulogne-Billancourt, FranceInfectious Diseases Department, APHP, Hôpital Tenon, Hôpitaux Universitaires Paris-Est, Paris, FranceInfectious Diseases Department, APHP, Hôpital Bichat Claude Bernard, Paris, FranceInfectious Diseases Department, APHP, Hôpital Bichat Claude Bernard, Paris, FranceInfectious Diseases Department, APHP, Hôpital Saint-Antoine, Paris, FranceDermatology Department, APHP, Hôpital Bichat Claude Bernard, Paris, FranceInfectious Diseases Department, APHP, Hôpital Saint-Louis, Paris, FranceInfectious Diseases Department, APHP, Hôpital Avicenne, Bobigny, FranceInfectious Diseases Department, APHP, CHU Bicêtre, Le Kremlin Bicêtre, FranceService de Médecine Interne, Centre Hospitalier Intercommunal de Créteil, Créteil, FranceResearch Group Dynamic, EA7380, Faculté de Santé de Créteil, Ecole Nationale Vétérinaire d’Alfort, USC ANSES, Université Paris-Est Créteil, Créteil, FranceResearch Group Dynamic, EA7380, Faculté de Santé de Créteil, Ecole Nationale Vétérinaire d’Alfort, USC ANSES, Université Paris-Est Créteil, Créteil, FranceDermatology Department, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Henri-Mondor, Créteil, FranceDermatology Department, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Henri-Mondor, Créteil, FranceThe aim of this multi-centre French retrospective study was to identify severe, i.e. crusted and profuse, scabies patients. Records were retrieved from 22 Dermatology or Infectious Diseases departments in the Ile-de-France from January 2009 to January 2015 to characterize epidemiology, demography, diagnosis, contributing factors, treatment features, and outcomes in severe scabies. A total of 95 inpatients (57 crusted and 38 profuse) were included. A higher number of cases was observed among elderly patients (>75 years), mostly living in institutions. Thirteen patients (13.6%) reported a history of previously treated scabies. Sixty-three patients (66.3%) had been seen by a previous practitioner for the current episode (up to 8 previous visits). Initial misdiagnosis (e.g. eczema, prurigo, drug-related eruptions, psoriasis) was documented in 41 patients (43.1%). Fifty-eight patients (61%) had already received 1 or more previous treatments for their current episode. Forty percent received corticosteroids or acitretin for an initial diagnosis of eczema or psoriasis. Median time from the onset of symptoms to the diagnosis of severe scabies was 3 months (range 0.3–22). Itch was present in all patients at diagnosis. Most patients (n=84, 88.4%) had comorbidities. Diagnostic and therapeutic approaches varied. Complications occurred in 11.5% of cases. To date, there is no consensus for diagnosis and treatment, and future standardization of is required for optimal management. https://medicaljournalssweden.se/actadv/article/view/5351scabiesSarcoptes scabieiparasiticcrusted scabiespruritusivermectin |
| spellingShingle | Charbel Skayem Askour Majda Charlotte Gary Francois Hemery Emmanuel Mahé Frederic Caux Nicolas Dupin Patricia Senet Alix Greder-Belan Brigitte Hillion Cecile Meni Philippe Saiag Guillaume Bellaud Alexandre Bleibtreu Sylvie Lariven Diane Bollens Vincent Descamps Jean-Michel Molina Olivier Bouchaud Daniel Vittecoq Gia Do-Pham Francoise Foulet Francoise Botterel Olivier Chosidow Charlotte Bernigaud Severe Scabies: A French Multi-centre Study Involving 95 Patients with Crusted and Profuse Disease and Review of the Literature Acta Dermato-Venereologica scabies Sarcoptes scabiei parasitic crusted scabies pruritus ivermectin |
| title | Severe Scabies: A French Multi-centre Study Involving 95 Patients with Crusted and Profuse Disease and Review of the Literature |
| title_full | Severe Scabies: A French Multi-centre Study Involving 95 Patients with Crusted and Profuse Disease and Review of the Literature |
| title_fullStr | Severe Scabies: A French Multi-centre Study Involving 95 Patients with Crusted and Profuse Disease and Review of the Literature |
| title_full_unstemmed | Severe Scabies: A French Multi-centre Study Involving 95 Patients with Crusted and Profuse Disease and Review of the Literature |
| title_short | Severe Scabies: A French Multi-centre Study Involving 95 Patients with Crusted and Profuse Disease and Review of the Literature |
| title_sort | severe scabies a french multi centre study involving 95 patients with crusted and profuse disease and review of the literature |
| topic | scabies Sarcoptes scabiei parasitic crusted scabies pruritus ivermectin |
| url | https://medicaljournalssweden.se/actadv/article/view/5351 |
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