Incidental primary breast cancer detected on surveillance 68Ga-DOTATATE PET/CT in a patient with metastatic neuroendocrine carcinoma
We present a case of a 53-year-old woman with metastatic neuroendocrine tumor, presumed primary in the small intestine with metastases to the liver and mesenteric lymph nodes. The patient was being treated with lanreotide and followed with somatostatin receptor (SSTR)-targeted 68Ga-labeled 1,4,7,10-...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-08-01
|
| Series: | Radiology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043320302302 |
| _version_ | 1818352681778937856 |
|---|---|
| author | Emily B. Ambinder, MD Rudolf A. Werner, MD Steven P. Rowe, MD, PhD |
| author_facet | Emily B. Ambinder, MD Rudolf A. Werner, MD Steven P. Rowe, MD, PhD |
| author_sort | Emily B. Ambinder, MD |
| collection | DOAJ |
| description | We present a case of a 53-year-old woman with metastatic neuroendocrine tumor, presumed primary in the small intestine with metastases to the liver and mesenteric lymph nodes. The patient was being treated with lanreotide and followed with somatostatin receptor (SSTR)-targeted 68Ga-labeled 1,4,7,10-tetraazacyclododecane-N,N', N'',N'''-tetraacetic acid-d-Phe(1)-Tyr(3)-octreotate (68Ga-DOTATATE) positron emission tomography – computed tomography (PET/CT). On a follow-up exam, the patient's primary and metastatic disease had improved but she had new 68Ga-DOTATATE-avid lesions in the right breast and right axilla. Subsequent breast imaging workup and biopsy demonstrated a primary breast cancer and axillary lymph node metastasis. |
| first_indexed | 2024-12-13T18:57:30Z |
| format | Article |
| id | doaj.art-6f6dd07996f242119ead7f54e4f8381b |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-12-13T18:57:30Z |
| publishDate | 2020-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-6f6dd07996f242119ead7f54e4f8381b2022-12-21T23:34:46ZengElsevierRadiology Case Reports1930-04332020-08-0115813441347Incidental primary breast cancer detected on surveillance 68Ga-DOTATATE PET/CT in a patient with metastatic neuroendocrine carcinomaEmily B. Ambinder, MD0Rudolf A. Werner, MD1Steven P. Rowe, MD, PhD2Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 601 N. Caroline Street, Baltimore 21287, MD, USA; Corresponding author.Department of Nuclear Medicine, Hannover Medical School, Hannover, GermanyRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 601 N. Caroline Street, Baltimore 21287, MD, USAWe present a case of a 53-year-old woman with metastatic neuroendocrine tumor, presumed primary in the small intestine with metastases to the liver and mesenteric lymph nodes. The patient was being treated with lanreotide and followed with somatostatin receptor (SSTR)-targeted 68Ga-labeled 1,4,7,10-tetraazacyclododecane-N,N', N'',N'''-tetraacetic acid-d-Phe(1)-Tyr(3)-octreotate (68Ga-DOTATATE) positron emission tomography – computed tomography (PET/CT). On a follow-up exam, the patient's primary and metastatic disease had improved but she had new 68Ga-DOTATATE-avid lesions in the right breast and right axilla. Subsequent breast imaging workup and biopsy demonstrated a primary breast cancer and axillary lymph node metastasis.http://www.sciencedirect.com/science/article/pii/S1930043320302302Breast neoplasmDotatate PET/CTSomatostatin receptor imagingNeuroendocrine carcinoma |
| spellingShingle | Emily B. Ambinder, MD Rudolf A. Werner, MD Steven P. Rowe, MD, PhD Incidental primary breast cancer detected on surveillance 68Ga-DOTATATE PET/CT in a patient with metastatic neuroendocrine carcinoma Radiology Case Reports Breast neoplasm Dotatate PET/CT Somatostatin receptor imaging Neuroendocrine carcinoma |
| title | Incidental primary breast cancer detected on surveillance 68Ga-DOTATATE PET/CT in a patient with metastatic neuroendocrine carcinoma |
| title_full | Incidental primary breast cancer detected on surveillance 68Ga-DOTATATE PET/CT in a patient with metastatic neuroendocrine carcinoma |
| title_fullStr | Incidental primary breast cancer detected on surveillance 68Ga-DOTATATE PET/CT in a patient with metastatic neuroendocrine carcinoma |
| title_full_unstemmed | Incidental primary breast cancer detected on surveillance 68Ga-DOTATATE PET/CT in a patient with metastatic neuroendocrine carcinoma |
| title_short | Incidental primary breast cancer detected on surveillance 68Ga-DOTATATE PET/CT in a patient with metastatic neuroendocrine carcinoma |
| title_sort | incidental primary breast cancer detected on surveillance 68ga dotatate pet ct in a patient with metastatic neuroendocrine carcinoma |
| topic | Breast neoplasm Dotatate PET/CT Somatostatin receptor imaging Neuroendocrine carcinoma |
| url | http://www.sciencedirect.com/science/article/pii/S1930043320302302 |
| work_keys_str_mv | AT emilybambindermd incidentalprimarybreastcancerdetectedonsurveillance68gadotatatepetctinapatientwithmetastaticneuroendocrinecarcinoma AT rudolfawernermd incidentalprimarybreastcancerdetectedonsurveillance68gadotatatepetctinapatientwithmetastaticneuroendocrinecarcinoma AT stevenprowemdphd incidentalprimarybreastcancerdetectedonsurveillance68gadotatatepetctinapatientwithmetastaticneuroendocrinecarcinoma |