Antimicrobial Activity of Selected Ethnoveterinary Medicinal Plants of Southern Region, Ethiopia
Tegegn Dilbato Dinbiso,1 Feyissa Begna Deressa,2 Diriba Tadesse Legesse,2 Eshetu Shumi Gebisa,2 Alemayehu Choramo Diko,3 Tadele Tolosa Fulasa2 1School of Veterinary Medicine, Department of Veterinary Science, Ambo University, Guder Mamo Mezemir Campus, Ambo, Ethiopia; 2School of Veterinary Medicine,...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2022-10-01
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| Series: | Infection and Drug Resistance |
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| Online Access: | https://www.dovepress.com/antimicrobial-activity-of-selected-ethnoveterinary-medicinal-plants-of-peer-reviewed-fulltext-article-IDR |
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| author | Dilbato Dinbiso T Deressa FB Legesse DT Shumi Gebisa E Choramo Diko A Tolosa Fulasa T |
| author_facet | Dilbato Dinbiso T Deressa FB Legesse DT Shumi Gebisa E Choramo Diko A Tolosa Fulasa T |
| author_sort | Dilbato Dinbiso T |
| collection | DOAJ |
| description | Tegegn Dilbato Dinbiso,1 Feyissa Begna Deressa,2 Diriba Tadesse Legesse,2 Eshetu Shumi Gebisa,2 Alemayehu Choramo Diko,3 Tadele Tolosa Fulasa2 1School of Veterinary Medicine, Department of Veterinary Science, Ambo University, Guder Mamo Mezemir Campus, Ambo, Ethiopia; 2School of Veterinary Medicine, Jimma University College of Agriculture and Veterinary Medicine, Jimma, Ethiopia; 3School of Veterinary Medicine, Bonga University College of Agriculture and Natural Resource, Bonga, EthiopiaCorrespondence: Alemayehu Choramo Diko, Tel +251917106238 ; +251 966889055, Email alexchoramo@gmail.comBackground: For decades, Ethiopians have employed ethnoveterinary medicinal plants to cure both human and livestock ailments. Currently, few studies have been conducted on antimicrobial activity evaluation in Ethiopia. This study, therefore, is designed to evaluate the antibacterial activities of selected ethnoveterinary medicinal plants used in treating livestock ailments in the study area.Methods: Ethanol extracts of plants obtained by maceration of roots and leaves of four medicinal plant species were studied for potential antimicrobial activity using a disc diffusion method against S. aureus and E. coli. Data obtained from experiments were analyzed using ANOVA and the significant test was set to P < 0.05.Results: The antibacterial properties of four ethanol extracts of leaves of Withania somnifera L., Becium obovatum, Ageratum conyzoides L., and root of Pentas lanceolata (Forssk.) Defiers were evaluated in vitro and found to be effective against S. aureus but not E. coli. There was no significant difference between the studied plant species and concentrations (p > 0.05), according to the results. The four test extracts had minimum inhibitory concentrations (MICs) ranging from 6.25 to 25 mg/mL, with inhibitory potential ranging from 12.5 to 100 mg/mL. Pentas lanceolata (Forssk.) Defiers’s antibacterial activity at a concentration of 100 mg/mL (18.67 3.78 mm) was comparable to the standard antibiotic (Gentamicin 20g per disc), which had a measurement of 23.08 ± 0.9 mm.Conclusion: This finding on the selected medicinal plants of Dawuro Zone supports the traditional claims of effective antimicrobial activity in the treatment of livestock health management. Hence, the study suggests further investigations need to be conducted to isolate and elucidate active ingredients in the plant materials tested.Keywords: antibacterial activity, Dawuro zone, extraction, medicinal plant, maceration |
| first_indexed | 2024-04-13T17:22:18Z |
| format | Article |
| id | doaj.art-6f727640a80542738db3a59d5562d479 |
| institution | Directory Open Access Journal |
| issn | 1178-6973 |
| language | English |
| last_indexed | 2024-04-13T17:22:18Z |
| publishDate | 2022-10-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Infection and Drug Resistance |
| spelling | doaj.art-6f727640a80542738db3a59d5562d4792022-12-22T02:37:55ZengDove Medical PressInfection and Drug Resistance1178-69732022-10-01Volume 156225623579263Antimicrobial Activity of Selected Ethnoveterinary Medicinal Plants of Southern Region, EthiopiaDilbato Dinbiso TDeressa FBLegesse DTShumi Gebisa EChoramo Diko ATolosa Fulasa TTegegn Dilbato Dinbiso,1 Feyissa Begna Deressa,2 Diriba Tadesse Legesse,2 Eshetu Shumi Gebisa,2 Alemayehu Choramo Diko,3 Tadele Tolosa Fulasa2 1School of Veterinary Medicine, Department of Veterinary Science, Ambo University, Guder Mamo Mezemir Campus, Ambo, Ethiopia; 2School of Veterinary Medicine, Jimma University College of Agriculture and Veterinary Medicine, Jimma, Ethiopia; 3School of Veterinary Medicine, Bonga University College of Agriculture and Natural Resource, Bonga, EthiopiaCorrespondence: Alemayehu Choramo Diko, Tel +251917106238 ; +251 966889055, Email alexchoramo@gmail.comBackground: For decades, Ethiopians have employed ethnoveterinary medicinal plants to cure both human and livestock ailments. Currently, few studies have been conducted on antimicrobial activity evaluation in Ethiopia. This study, therefore, is designed to evaluate the antibacterial activities of selected ethnoveterinary medicinal plants used in treating livestock ailments in the study area.Methods: Ethanol extracts of plants obtained by maceration of roots and leaves of four medicinal plant species were studied for potential antimicrobial activity using a disc diffusion method against S. aureus and E. coli. Data obtained from experiments were analyzed using ANOVA and the significant test was set to P < 0.05.Results: The antibacterial properties of four ethanol extracts of leaves of Withania somnifera L., Becium obovatum, Ageratum conyzoides L., and root of Pentas lanceolata (Forssk.) Defiers were evaluated in vitro and found to be effective against S. aureus but not E. coli. There was no significant difference between the studied plant species and concentrations (p > 0.05), according to the results. The four test extracts had minimum inhibitory concentrations (MICs) ranging from 6.25 to 25 mg/mL, with inhibitory potential ranging from 12.5 to 100 mg/mL. Pentas lanceolata (Forssk.) Defiers’s antibacterial activity at a concentration of 100 mg/mL (18.67 3.78 mm) was comparable to the standard antibiotic (Gentamicin 20g per disc), which had a measurement of 23.08 ± 0.9 mm.Conclusion: This finding on the selected medicinal plants of Dawuro Zone supports the traditional claims of effective antimicrobial activity in the treatment of livestock health management. Hence, the study suggests further investigations need to be conducted to isolate and elucidate active ingredients in the plant materials tested.Keywords: antibacterial activity, Dawuro zone, extraction, medicinal plant, macerationhttps://www.dovepress.com/antimicrobial-activity-of-selected-ethnoveterinary-medicinal-plants-of-peer-reviewed-fulltext-article-IDRantibacterial activitydawuro zoneextractionmedicinal plantmaceration |
| spellingShingle | Dilbato Dinbiso T Deressa FB Legesse DT Shumi Gebisa E Choramo Diko A Tolosa Fulasa T Antimicrobial Activity of Selected Ethnoveterinary Medicinal Plants of Southern Region, Ethiopia Infection and Drug Resistance antibacterial activity dawuro zone extraction medicinal plant maceration |
| title | Antimicrobial Activity of Selected Ethnoveterinary Medicinal Plants of Southern Region, Ethiopia |
| title_full | Antimicrobial Activity of Selected Ethnoveterinary Medicinal Plants of Southern Region, Ethiopia |
| title_fullStr | Antimicrobial Activity of Selected Ethnoveterinary Medicinal Plants of Southern Region, Ethiopia |
| title_full_unstemmed | Antimicrobial Activity of Selected Ethnoveterinary Medicinal Plants of Southern Region, Ethiopia |
| title_short | Antimicrobial Activity of Selected Ethnoveterinary Medicinal Plants of Southern Region, Ethiopia |
| title_sort | antimicrobial activity of selected ethnoveterinary medicinal plants of southern region ethiopia |
| topic | antibacterial activity dawuro zone extraction medicinal plant maceration |
| url | https://www.dovepress.com/antimicrobial-activity-of-selected-ethnoveterinary-medicinal-plants-of-peer-reviewed-fulltext-article-IDR |
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