CD157 Confers Host Resistance to <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> via TLR2-CD157-PKCzeta-Induced Reactive Oxygen Species Production

CD157 Confers Host Resistance to <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> via TLR2-CD157-PKCzeta-Induced Reactive Oxygen Species Production

ABSTRACT Recruitment of monocytes to the infection site is critical for host resistance against Mycobacterium tuberculosis. CD157 has a crucial role in neutrophil and monocyte transendothelial migration and adhesion, but its role in tuberculosis (TB) is unclear. Here, we show that both mRNA and prot...

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Bibliographic Details
Main Authors: Qianting Yang, Mingfeng Liao, Wenfei Wang, Mingxia Zhang, Qi Chen, Jiubiao Guo, Bin Peng, Jian Huang, Haiying Liu, Ayano Yahagi, Xingzhi Xu, Katsuhiko Ishihara, Andrea Cooper, Xinchun Chen, Yi Cai
Format: Article
Language:English
Published: American Society for Microbiology 2019-08-01
Series:mBio
Subjects:
CD157
Mycobacterium tuberculosis
PKCzeta
TLR2
reactive oxygen species
Online Access:https://journals.asm.org/doi/10.1128/mBio.01949-19

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