A Novel Resolution of Diabetes: C-C Chemokine Motif Ligand 4 Is a Common Target in Different Types of Diabetes by Protecting Pancreatic Islet Cell and Modulating Inflammation
Systemic inflammation is related to hyperglycemia in diabetes mellitus (DM). C-C chemokine motif ligand (CCL) 4 is upregulated in type 1 & type 2 DM patients. This study aimed to investigate if CCL4 could be a potential target to improve blood sugar control in different experimental DM model...
Main Authors: | Ting-Ting Chang, Liang-Yu Lin, Jaw-Wen Chen |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-04-01
|
Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2021.650626/full |
Similar Items
-
CCL7 as a novel inflammatory mediator in cardiovascular disease, diabetes mellitus, and kidney disease
by: Ting-Ting Chang, et al.
Published: (2022-09-01) -
CCL4 Deletion Accelerates Wound Healing by Improving Endothelial Cell Functions in Diabetes Mellitus
by: Ting-Ting Chang, et al.
Published: (2022-08-01) -
C–C motif chemokine ligand 2/C–C motif chemokine receptor 2 pathway as a therapeutic target and regulatory mechanism for spinal cord injury
by: Xiangzi Wang, et al.
Published: (2025-08-01) -
α1‐Adrenergic Receptors Function Within Hetero‐Oligomeric Complexes With Atypical Chemokine Receptor 3 and Chemokine (C‐X‐C motif) Receptor 4 in Vascular Smooth Muscle Cells
by: Lauren J. Albee, et al.
Published: (2017-08-01) -
The prognostic value of C-X-C motif chemokine receptor 4 in patients with sporadic malignant peripheral nerve sheath tumors
by: Chao Zhang, et al.
Published: (2017-10-01)