Differential Diagnosis of Urticarial Lesions
Urticaria is a mast cell-dependent disease, characterized by the presence of wheals, angioedema, or both in the absence of systemic symptoms. It is a common disease worldwide, with an important health burden especially in chronic situations, that last more than 6 weeks. Although urticaria is usually...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-06-01
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| Series: | Frontiers in Allergy |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/falgy.2022.808543/full |
| _version_ | 1811246166676865024 |
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| author | Ana Luísa Matos Carolina Figueiredo Margarida Gonçalo Margarida Gonçalo |
| author_facet | Ana Luísa Matos Carolina Figueiredo Margarida Gonçalo Margarida Gonçalo |
| author_sort | Ana Luísa Matos |
| collection | DOAJ |
| description | Urticaria is a mast cell-dependent disease, characterized by the presence of wheals, angioedema, or both in the absence of systemic symptoms. It is a common disease worldwide, with an important health burden especially in chronic situations, that last more than 6 weeks. Although urticaria is usually a straightforward diagnosis, some diseases presenting with urticarial lesions must be excluded, particularly urticarial vasculitis and auto-inflammatory syndromes. In these settings additional atypical features are often present (long-lasting lesions, bruising, fever, malaise, arthralgia), allowing the clinician to suspect a diagnosis other than urticaria. The authors propose an approach based on these atypical features, the presence or absence of systemic symptoms and on skin histopathology as well as some blood parameters. |
| first_indexed | 2024-04-12T14:49:46Z |
| format | Article |
| id | doaj.art-6f7996bcf1bd404e8bae8528d77bfa69 |
| institution | Directory Open Access Journal |
| issn | 2673-6101 |
| language | English |
| last_indexed | 2024-04-12T14:49:46Z |
| publishDate | 2022-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Allergy |
| spelling | doaj.art-6f7996bcf1bd404e8bae8528d77bfa692022-12-22T03:28:30ZengFrontiers Media S.A.Frontiers in Allergy2673-61012022-06-01310.3389/falgy.2022.808543808543Differential Diagnosis of Urticarial LesionsAna Luísa Matos0Carolina Figueiredo1Margarida Gonçalo2Margarida Gonçalo3Dermatology Department, Coimbra University Hospital Center, Coimbra, PortugalDermatology Department, Coimbra University Hospital Center, Coimbra, PortugalDermatology Department, Coimbra University Hospital Center, Coimbra, PortugalFaculty of Medicine, Dermatology Department, University of Coimbra, Coimbra, PortugalUrticaria is a mast cell-dependent disease, characterized by the presence of wheals, angioedema, or both in the absence of systemic symptoms. It is a common disease worldwide, with an important health burden especially in chronic situations, that last more than 6 weeks. Although urticaria is usually a straightforward diagnosis, some diseases presenting with urticarial lesions must be excluded, particularly urticarial vasculitis and auto-inflammatory syndromes. In these settings additional atypical features are often present (long-lasting lesions, bruising, fever, malaise, arthralgia), allowing the clinician to suspect a diagnosis other than urticaria. The authors propose an approach based on these atypical features, the presence or absence of systemic symptoms and on skin histopathology as well as some blood parameters.https://www.frontiersin.org/articles/10.3389/falgy.2022.808543/fullurticariaangioedemaurticarial syndromesautoinflammatory syndromeschronic spontaneous urticaria |
| spellingShingle | Ana Luísa Matos Carolina Figueiredo Margarida Gonçalo Margarida Gonçalo Differential Diagnosis of Urticarial Lesions Frontiers in Allergy urticaria angioedema urticarial syndromes autoinflammatory syndromes chronic spontaneous urticaria |
| title | Differential Diagnosis of Urticarial Lesions |
| title_full | Differential Diagnosis of Urticarial Lesions |
| title_fullStr | Differential Diagnosis of Urticarial Lesions |
| title_full_unstemmed | Differential Diagnosis of Urticarial Lesions |
| title_short | Differential Diagnosis of Urticarial Lesions |
| title_sort | differential diagnosis of urticarial lesions |
| topic | urticaria angioedema urticarial syndromes autoinflammatory syndromes chronic spontaneous urticaria |
| url | https://www.frontiersin.org/articles/10.3389/falgy.2022.808543/full |
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