Thrombotic thrombocytopenic purpura due to varicella-zoster virus meningoencephalitis in an immunocompetent patient

Varicella-zoster virus (VZV) can cause variable disease states in individuals with intact and compromised immune systems. Both meningoencephalitis and thrombotic thrombocytopenic purpura (TTP) are uncommon, life-threatening entities associated with VZV. There are few reported cases of TTP due to VZV...

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Main Authors: Zachary Mostel, Ben Anthony Nguyen, Louis Costanzo, Sarah Bankhead, Parinaz Ayat, Harsha Taluru, Anoop Puskoor, Zahra Ahmed, Edwin Chiu, Adam El Sehamy, David Nathaniel Smith
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Journal of Global Infectious Diseases
Subjects:
Online Access:http://www.jgid.org/article.asp?issn=0974-777X;year=2023;volume=15;issue=4;spage=172;epage=174;aulast=Mostel
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author Zachary Mostel
Ben Anthony Nguyen
Louis Costanzo
Sarah Bankhead
Parinaz Ayat
Harsha Taluru
Anoop Puskoor
Zahra Ahmed
Edwin Chiu
Adam El Sehamy
David Nathaniel Smith
author_facet Zachary Mostel
Ben Anthony Nguyen
Louis Costanzo
Sarah Bankhead
Parinaz Ayat
Harsha Taluru
Anoop Puskoor
Zahra Ahmed
Edwin Chiu
Adam El Sehamy
David Nathaniel Smith
author_sort Zachary Mostel
collection DOAJ
description Varicella-zoster virus (VZV) can cause variable disease states in individuals with intact and compromised immune systems. Both meningoencephalitis and thrombotic thrombocytopenic purpura (TTP) are uncommon, life-threatening entities associated with VZV. There are few reported cases of TTP due to VZV and this may be the first case of TTP due to VZV meningoencephalitis confirmed through lumbar puncture. The literature tends to emphasize that this pathology mostly occurs in immunocompromised hosts. Here, we present a unique case of TTP due to VZV meningoencephalitis in a patient that was immunocompetent.
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spelling doaj.art-6f7fcc4484e94a00ba6cf480d807ca6f2024-04-01T06:01:36ZengWolters Kluwer Medknow PublicationsJournal of Global Infectious Diseases0974-777X2023-01-0115417217410.4103/jgid.jgid_241_22Thrombotic thrombocytopenic purpura due to varicella-zoster virus meningoencephalitis in an immunocompetent patientZachary MostelBen Anthony NguyenLouis CostanzoSarah BankheadParinaz AyatHarsha TaluruAnoop PuskoorZahra AhmedEdwin ChiuAdam El SehamyDavid Nathaniel SmithVaricella-zoster virus (VZV) can cause variable disease states in individuals with intact and compromised immune systems. Both meningoencephalitis and thrombotic thrombocytopenic purpura (TTP) are uncommon, life-threatening entities associated with VZV. There are few reported cases of TTP due to VZV and this may be the first case of TTP due to VZV meningoencephalitis confirmed through lumbar puncture. The literature tends to emphasize that this pathology mostly occurs in immunocompromised hosts. Here, we present a unique case of TTP due to VZV meningoencephalitis in a patient that was immunocompetent.http://www.jgid.org/article.asp?issn=0974-777X;year=2023;volume=15;issue=4;spage=172;epage=174;aulast=Mostelmeningoencephalitisthrombotic thrombocytopenic purpuravaricella zoster virus
spellingShingle Zachary Mostel
Ben Anthony Nguyen
Louis Costanzo
Sarah Bankhead
Parinaz Ayat
Harsha Taluru
Anoop Puskoor
Zahra Ahmed
Edwin Chiu
Adam El Sehamy
David Nathaniel Smith
Thrombotic thrombocytopenic purpura due to varicella-zoster virus meningoencephalitis in an immunocompetent patient
Journal of Global Infectious Diseases
meningoencephalitis
thrombotic thrombocytopenic purpura
varicella zoster virus
title Thrombotic thrombocytopenic purpura due to varicella-zoster virus meningoencephalitis in an immunocompetent patient
title_full Thrombotic thrombocytopenic purpura due to varicella-zoster virus meningoencephalitis in an immunocompetent patient
title_fullStr Thrombotic thrombocytopenic purpura due to varicella-zoster virus meningoencephalitis in an immunocompetent patient
title_full_unstemmed Thrombotic thrombocytopenic purpura due to varicella-zoster virus meningoencephalitis in an immunocompetent patient
title_short Thrombotic thrombocytopenic purpura due to varicella-zoster virus meningoencephalitis in an immunocompetent patient
title_sort thrombotic thrombocytopenic purpura due to varicella zoster virus meningoencephalitis in an immunocompetent patient
topic meningoencephalitis
thrombotic thrombocytopenic purpura
varicella zoster virus
url http://www.jgid.org/article.asp?issn=0974-777X;year=2023;volume=15;issue=4;spage=172;epage=174;aulast=Mostel
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