Phytoconstituents from Sidastrum micranthum (A. St.-Hil.) Fryxell (Malvaceae) and antimicrobial activity of pheophytin a
abstract Sidastrum micranthum (A. St.-Hil.) Fryxell, a member of the Malvaceae family, is called malva preta in Brazil. As this species is commonly used to treat bronchitis, cough, and asthma, better knowledge of its chemical compounds is important. The phytochemical study of its hexane extract, usi...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Universidade de São Paulo
2015-12-01
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| Series: | Brazilian Journal of Pharmaceutical Sciences |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000400861&lng=en&tlng=en |
| _version_ | 1818755424020594688 |
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| author | Roosevelt Albuquerque Gomes Yanna Carolina Ferreira Teles Fillipe de Oliveira Pereira Luis Alberto de Sousa Rodrigues Edeltrudes de Oliveira Lima Maria de Fátima Agra Maria de Fátima Vanderlei de Souza |
| author_facet | Roosevelt Albuquerque Gomes Yanna Carolina Ferreira Teles Fillipe de Oliveira Pereira Luis Alberto de Sousa Rodrigues Edeltrudes de Oliveira Lima Maria de Fátima Agra Maria de Fátima Vanderlei de Souza |
| author_sort | Roosevelt Albuquerque Gomes |
| collection | DOAJ |
| description | abstract Sidastrum micranthum (A. St.-Hil.) Fryxell, a member of the Malvaceae family, is called malva preta in Brazil. As this species is commonly used to treat bronchitis, cough, and asthma, better knowledge of its chemical compounds is important. The phytochemical study of its hexane extract, using chromatographic techniques, led to isolation of six compounds: the triterpene isoarborinol, a mixture of sitosterol and stigmasterol, sitosterol-3-O-β-D-glucopyranoside, pheophytin a, and 132-hydroxy-(132-S)-pheophytin a. Structural identification of these compounds was carried out using spectroscopic methods such as IR and 1D and 2D NMR (HOMOCOSY, HMQC, HMBC, and NOESY). Compounds isolated from S. micranthum were screened for their in vitro antifungal and antibacterial activity against twenty fungal and bacterial standard strains. Pheophytin a exhibited antimicrobial action against all microorganisms tested. |
| first_indexed | 2024-12-18T05:38:55Z |
| format | Article |
| id | doaj.art-6f7fdf8dad914b6a8b5fc3eb93c62297 |
| institution | Directory Open Access Journal |
| issn | 2175-9790 |
| language | English |
| last_indexed | 2024-12-18T05:38:55Z |
| publishDate | 2015-12-01 |
| publisher | Universidade de São Paulo |
| record_format | Article |
| series | Brazilian Journal of Pharmaceutical Sciences |
| spelling | doaj.art-6f7fdf8dad914b6a8b5fc3eb93c622972022-12-21T21:19:13ZengUniversidade de São PauloBrazilian Journal of Pharmaceutical Sciences2175-97902015-12-0151486186710.1590/S1984-82502015000400012S1984-82502015000400861Phytoconstituents from Sidastrum micranthum (A. St.-Hil.) Fryxell (Malvaceae) and antimicrobial activity of pheophytin aRoosevelt Albuquerque GomesYanna Carolina Ferreira TelesFillipe de Oliveira PereiraLuis Alberto de Sousa RodriguesEdeltrudes de Oliveira LimaMaria de Fátima AgraMaria de Fátima Vanderlei de Souzaabstract Sidastrum micranthum (A. St.-Hil.) Fryxell, a member of the Malvaceae family, is called malva preta in Brazil. As this species is commonly used to treat bronchitis, cough, and asthma, better knowledge of its chemical compounds is important. The phytochemical study of its hexane extract, using chromatographic techniques, led to isolation of six compounds: the triterpene isoarborinol, a mixture of sitosterol and stigmasterol, sitosterol-3-O-β-D-glucopyranoside, pheophytin a, and 132-hydroxy-(132-S)-pheophytin a. Structural identification of these compounds was carried out using spectroscopic methods such as IR and 1D and 2D NMR (HOMOCOSY, HMQC, HMBC, and NOESY). Compounds isolated from S. micranthum were screened for their in vitro antifungal and antibacterial activity against twenty fungal and bacterial standard strains. Pheophytin a exhibited antimicrobial action against all microorganisms tested.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000400861&lng=en&tlng=enMalvaceae/fitoquímicaSidastrum micranthum/fitoquímicaSidastrum micranthum/atividade antimicrobiana/estudo in vitroFeofitinasPlantas medicinais. |
| spellingShingle | Roosevelt Albuquerque Gomes Yanna Carolina Ferreira Teles Fillipe de Oliveira Pereira Luis Alberto de Sousa Rodrigues Edeltrudes de Oliveira Lima Maria de Fátima Agra Maria de Fátima Vanderlei de Souza Phytoconstituents from Sidastrum micranthum (A. St.-Hil.) Fryxell (Malvaceae) and antimicrobial activity of pheophytin a Brazilian Journal of Pharmaceutical Sciences Malvaceae/fitoquímica Sidastrum micranthum/fitoquímica Sidastrum micranthum/atividade antimicrobiana/estudo in vitro Feofitinas Plantas medicinais. |
| title | Phytoconstituents from Sidastrum micranthum (A. St.-Hil.) Fryxell (Malvaceae) and antimicrobial activity of pheophytin a |
| title_full | Phytoconstituents from Sidastrum micranthum (A. St.-Hil.) Fryxell (Malvaceae) and antimicrobial activity of pheophytin a |
| title_fullStr | Phytoconstituents from Sidastrum micranthum (A. St.-Hil.) Fryxell (Malvaceae) and antimicrobial activity of pheophytin a |
| title_full_unstemmed | Phytoconstituents from Sidastrum micranthum (A. St.-Hil.) Fryxell (Malvaceae) and antimicrobial activity of pheophytin a |
| title_short | Phytoconstituents from Sidastrum micranthum (A. St.-Hil.) Fryxell (Malvaceae) and antimicrobial activity of pheophytin a |
| title_sort | phytoconstituents from sidastrum micranthum a st hil fryxell malvaceae and antimicrobial activity of pheophytin a |
| topic | Malvaceae/fitoquímica Sidastrum micranthum/fitoquímica Sidastrum micranthum/atividade antimicrobiana/estudo in vitro Feofitinas Plantas medicinais. |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000400861&lng=en&tlng=en |
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