$Orelabrutinib Combined With Lenalidomide and Immunochemotherapy for Relapsed/Refractory Primary Central Nervous System Lymphoma: A Retrospective Analysis of Case Series$

Orelabrutinib Combined With Lenalidomide and Immunochemotherapy for Relapsed/Refractory Primary Central Nervous System Lymphoma: A Retrospective Analysis of Case Series

BackgroundRelapsed/refractory (r/r) primary central nervous system lymphoma (PCNSL) is an intractable situation without sound treatment. Bruton’s tyrosine kinase (BTK) represents an attractive drug target in PCNSL. Orelabrutinib is a new-generation BTK inhibitor with high cerebrospinal fluid (CSF) c...

Full description

Bibliographic Details
Main Authors:	Chuanwei Yang, Yong Cui, Xiaohui Ren, Ming Li, Kefu Yu, Shaoping Shen, Haihui Jiang, Mingxiao Li, Xiaokang Zhang, Xuzhe Zhao, Qinghui Zhu, Song Lin
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-06-01
Series:	Frontiers in Oncology
Subjects:	Orelabrutinib safety efficacy relapsed/refractory primary central nervous system lymphoma genomic characteristics
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2022.901797/full

Similar Items

Classification of Progression Patterns in Glioblastoma: Analysis of Predictive Factors and Clinical Implications
by: Haihui Jiang, et al.
Published: (2020-11-01)

Differential Predictors and Clinical Implications Associated With Long-Term Survivors in IDH Wildtype and Mutant Glioblastoma
by: Haihui Jiang, et al.
Published: (2021-05-01)

A prognostic estimation model based on mRNA-sequence data for patients with oligodendroglioma
by: Qinghui Zhu, et al.
Published: (2022-12-01)

Corrigendum: Distinguishing Pseudoprogression From True Early Progression in Isocitrate Dehydrogenase Wild-Type Glioblastoma by Interrogating Clinical, Radiological and Molecular Features
by: Mingxiao Li, et al.
Published: (2021-05-01)

Distinguishing Pseudoprogression From True Early Progression in Isocitrate Dehydrogenase Wild-Type Glioblastoma by Interrogating Clinical, Radiological, and Molecular Features
by: Mingxiao Li, et al.
Published: (2021-04-01)

T2/FLAIR Abnormity Could be the Sign of Glioblastoma Dissemination
by: Mingxiao Li, et al.
Published: (2022-02-01)

Effect and Safety of Orelabrutinib and Lenalidomide Plus R-mini CDOP in Relapsed/Refractory Aggressive B-cell Non-Hodgkin Lymphoma
by: Ying Shang, et al.
Published: (2023-12-01)

Development of a UPLC-MS/MS method for the determination of orelabrutinib in rat plasma and its application in pharmacokinetics
by: Ya-nan Liu, et al.
Published: (2022-09-01)

Refined Temporal-to-Frontal Horn Shunt for Treatment of Trapped Temporal Horn After Surgery of Peri- or Intraventricular Tumor: A Case Series Study
by: Xiaohui Ren, et al.
Published: (2021-11-01)

Higher Cho/NAA Ratio in Postoperative Peritumoral Edema Zone Is Associated With Earlier Recurrence of Glioblastoma
by: Yong Cui, et al.
Published: (2020-12-01)

Y-shaped branched ventriculo-peritoneal shunt for adult multiloculated hydrocephalus
by: Xiaohui Ren, et al.
Published: (2022-04-01)

Hormonal Regulation in Shade Avoidance
by: Chuanwei Yang, et al.
Published: (2017-09-01)

A New Framework of Urban Serious Game to Empower the Smartness of Citizens
by: Yang Lin, et al.
Published: (2021-10-01)

Case report: Temozolomide induced hypermutation indicates an unfavorable response to immunotherapy in patient with gliomas
by: Jiapeng Liu, et al.
Published: (2024-04-01)

The prognostic role of circulating tumor cells in gastric cancer: A meta-analysis
by: Zuxi Li, et al.
Published: (2022-10-01)

Information retrieval with concept ontology for domain-specific text
by: Li, Haihui
Published: (2017)

Shade-induced nuclear localization of PIF7 is regulated by phosphorylation and 14-3-3 proteins in Arabidopsis
by: Xu Huang, et al.
Published: (2018-06-01)

Fixed-Time Adaptive Tracking Control for a Quadrotor Unmanned Aerial Vehicle with Input Saturation
by: Haihui Wang, et al.
Published: (2023-03-01)

Clinical features and risk factors of deep vein thrombosis in COVID-19 patients:a retrospective analysis of 1 771 hospitalized patients
by: ZHANG Xiaohua, et al.
Published: (2020-08-01)

Level set incorporated with an improved MRF model for unsupervised change detection for satellite images
by: Xiaokang Zhang, et al.
Published: (2017-01-01)

Optical Aberration Calibration and Correction of Photographic System Based on Wavefront Coding
by: Chuanwei Yao, et al.
Published: (2021-06-01)

Investigation of non-uniform oxidation based on a mechanochemical phase field model with nonlinear reaction kinetics and large inelastic deformation
by: Chen Lin, et al.
Published: (2023-07-01)

The Minimal Subcortical Electronic Threshold Predicts the Motor Deficit and Survivals in Non-Awake Surgery for Gliomas Involving the Motor Pathway
by: Xiaohui Ren, et al.
Published: (2022-03-01)

Interfacial properties of SiCf/SiC minicomposites with a scheelite coating
by: Na Ni, et al.
Published: (2022-12-01)

Inhibitory Role of the Mud Crab Short Neuropeptide F in Vitellogenesis and Oocyte Maturation via Autocrine/Paracrine Signaling
by: Chenchang Bao, et al.
Published: (2018-07-01)

Simultaneous Determination of Orelabrutinib, Zanubrutinib, Ibrutinib and Its Active Metabolite in Human Plasma Using LC-MS/MS
by: Lu-Ning Sun, et al.
Published: (2023-01-01)

Addition of BTK inhibitor orelabrutinib to rituximab improved anti-tumor effects in B cell lymphoma
by: Hui Yu, et al.
Published: (2021-06-01)

Validation of Land Cover Products Using Reliability Evaluation Methods
by: Wenzhong Shi, et al.
Published: (2015-06-01)

Phase-field simulation of austenite reversion in a Fe-9.6Ni-7.1Mn (at.%) martensitic steel governed by a coupled diffusional/displacive mechanism
by: Xing Zhang, et al.
Published: (2020-03-01)

Development and characterisation of a nanoparticle-based sensor & microneedle-based sensor for codeine monitoring
by: Zhang, Haihui
Published: (2023)

Altervalent cation-doped MCM-41 supported palladium catalysts and their catalytic properties
by: HAIHUI JIANG, et al.
Published: (2011-06-01)

DNA Methylation Inhibits the Expression of CFSH in Mud Crab
by: Qingling Jiang, et al.
Published: (2020-04-01)

An immunostimulatory dual-functional nanocarrier that improves cancer immunochemotherapy
by: Yichao Chen, et al.
Published: (2016-11-01)

Effects of tempering temperature on the microstructure evolution and mechanical properties of 16%Cr–5%Ni super martensitic stainless steel
by: Yisi Song, et al.
Published: (2023-05-01)

Joint-Module Health Status Recognition for an Unmanned Platform: A Time–Frequency Representation and Extraction Network-Based Approach
by: Songbai Zhu, et al.
Published: (2024-01-01)

Temperature and settlement characteristics of graded crushed-rock layer for runway engineering in permafrost regions.
by: Xiaolan Liu, et al.
Published: (2022-01-01)

Anisotropic elasticity and abnormal Poisson’s ratios in super-hard materials
by: Chuanwei Huang, et al.
Published: (2014-12-01)

Non-flavonoid phenolics from Averrhoa carambola fresh fruit
by: Xuchao Jia, et al.
Published: (2017-05-01)

Implementing caregiver management measures in general hospitals to prevent the COVID‐19 pandemic
by: Xiaoman Zhang, et al.
Published: (2023-05-01)

Identification of a Putative CFSH Receptor Inhibiting IAG Expression in Crabs
by: Fang Liu, et al.
Published: (2023-07-01)