Euphorane C, an unusual C17-norabietane diterpenoid from Euphorbia dracunculoides induces cell cycle arrest and apoptosis in human leukemia K562 cells

Euphorane C, an unusual C17-norabietane diterpenoid from Euphorbia dracunculoides induces cell cycle arrest and apoptosis in human leukemia K562 cells

Four new polycyclic diterpenoids euphoranes A − D (1–4), together with 12 known terpenoids (5–16) were isolated from the whole plants of Euphorbia dracunculoides. Compound 2 represents the first example of aromatic 15,16,17-trinorabietane diterpenoid in Euphorbia species, and euphorane C (3) is an u...

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Bibliographic Details
Main Authors: Xue-Long Yan, Ming-Feng Zou, Bei-Ling Chen, Fang-Yu Yuan, Qin-Feng Zhu, Xu Zhang, Yan Lin, Qing-De Long, Wu-Ling Liu, Shang-Gao Liao
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Arabian Journal of Chemistry
Subjects:
Euphorbia dracunculoides
Cytotoxicity
Apoptosis
Abietane diterpenoid
Norabietane
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535222005196

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