Immunization with DAT fragments is associated with long-term striatal impairment, hyperactivity and reduced cognitive flexibility in mice

Immunization with DAT fragments is associated with long-term striatal impairment, hyperactivity and reduced cognitive flexibility in mice

<p>Abstract</p> <p>Background</p> <p>Possible interactions between nervous and immune systems in neuro-psychiatric disorders remain elusive. Levels of brain dopamine transporter (DAT) have been implicated in several impulse-control disorders, like attention deficit / hy...

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Bibliographic Details
Main Authors: Adriani Walter, Koot Susanne, Columba-Cabezas Sandra, Romano Emilia, Travaglini Domenica, van den Bos Ruud, Granstrem Oleg, Ali Syed F, Laviola Giovanni
Format: Article
Language:English
Published: BMC 2012-11-01
Series:Behavioral and Brain Functions
Subjects:
Auto-antibodies to neuro-receptors
DAT
Delay of reward
Flexibility of choice behaviour
ADHD
OCD
Online Access:http://www.behavioralandbrainfunctions.com/content/8/1/54

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