Low Iodine Diet for Preparation for Radioactive Iodine Therapy in Differentiated Thyroid Carcinoma in Korea
Preparation for radioactive iodine (RAI) therapy includes an increased serum thyroid stimulating hormone level and a low iodine diet (LID). Because of extremely high iodine intake, some physicians have advocated a more stringent LID for greater than 2 weeks in Korean patients with thyroid cancer pri...
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| Format: | Article |
| Language: | English |
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Korean Endocrine Society
2013-09-01
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| Series: | Endocrinology and Metabolism |
| Subjects: | |
| Online Access: | http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-28-157.pdf |
| _version_ | 1828315275157569536 |
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| author | Jae Hoon Chung |
| author_facet | Jae Hoon Chung |
| author_sort | Jae Hoon Chung |
| collection | DOAJ |
| description | Preparation for radioactive iodine (RAI) therapy includes an increased serum thyroid stimulating hormone level and a low iodine diet (LID). Because of extremely high iodine intake, some physicians have advocated a more stringent LID for greater than 2 weeks in Korean patients with thyroid cancer prior to RAI therapy; however, it is very difficult to maintain a stringent LID for a longer period of time. According to recent reports in Korea, a nonstringent, simple LID for only 1 week might be enough prior to RAI therapy, if the patients can be educated intensively by specially trained staff. The measurement of simple urinary iodine concentration (UIC; µg/L) may underestimate daily iodine excretion in patients with a urinary volume of more than 1 L/day and can also be affected by dilution status. Simple UIC had a weaker correlation than the iodine/creatinine (I/Cr) ratio. Therefore, the urinary I/Cr ratio can replace 24-hour urine iodine excretion instead of simple UIC, although it may overestimate iodine intake in patients with malnutrition or poor muscle mass. The measurement of serum iodine level might be useful as an adjunct parameter for assessing LID preparation, but its sensitivity and specificity were relatively low compared to the urinary I/Cr ratio. |
| first_indexed | 2024-04-13T16:57:45Z |
| format | Article |
| id | doaj.art-6f8594217a5747e0a72c72c6547b97db |
| institution | Directory Open Access Journal |
| issn | 2093-596X 2093-5978 |
| language | English |
| last_indexed | 2024-04-13T16:57:45Z |
| publishDate | 2013-09-01 |
| publisher | Korean Endocrine Society |
| record_format | Article |
| series | Endocrinology and Metabolism |
| spelling | doaj.art-6f8594217a5747e0a72c72c6547b97db2022-12-22T02:38:46ZengKorean Endocrine SocietyEndocrinology and Metabolism2093-596X2093-59782013-09-0128315716310.3803/EnM.2013.28.3.15721938Low Iodine Diet for Preparation for Radioactive Iodine Therapy in Differentiated Thyroid Carcinoma in KoreaJae Hoon ChungPreparation for radioactive iodine (RAI) therapy includes an increased serum thyroid stimulating hormone level and a low iodine diet (LID). Because of extremely high iodine intake, some physicians have advocated a more stringent LID for greater than 2 weeks in Korean patients with thyroid cancer prior to RAI therapy; however, it is very difficult to maintain a stringent LID for a longer period of time. According to recent reports in Korea, a nonstringent, simple LID for only 1 week might be enough prior to RAI therapy, if the patients can be educated intensively by specially trained staff. The measurement of simple urinary iodine concentration (UIC; µg/L) may underestimate daily iodine excretion in patients with a urinary volume of more than 1 L/day and can also be affected by dilution status. Simple UIC had a weaker correlation than the iodine/creatinine (I/Cr) ratio. Therefore, the urinary I/Cr ratio can replace 24-hour urine iodine excretion instead of simple UIC, although it may overestimate iodine intake in patients with malnutrition or poor muscle mass. The measurement of serum iodine level might be useful as an adjunct parameter for assessing LID preparation, but its sensitivity and specificity were relatively low compared to the urinary I/Cr ratio.http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-28-157.pdfRadioactive iodineIodineLow iodine dietUrinary iodine concentrationUrinary iodine excretion |
| spellingShingle | Jae Hoon Chung Low Iodine Diet for Preparation for Radioactive Iodine Therapy in Differentiated Thyroid Carcinoma in Korea Endocrinology and Metabolism Radioactive iodine Iodine Low iodine diet Urinary iodine concentration Urinary iodine excretion |
| title | Low Iodine Diet for Preparation for Radioactive Iodine Therapy in Differentiated Thyroid Carcinoma in Korea |
| title_full | Low Iodine Diet for Preparation for Radioactive Iodine Therapy in Differentiated Thyroid Carcinoma in Korea |
| title_fullStr | Low Iodine Diet for Preparation for Radioactive Iodine Therapy in Differentiated Thyroid Carcinoma in Korea |
| title_full_unstemmed | Low Iodine Diet for Preparation for Radioactive Iodine Therapy in Differentiated Thyroid Carcinoma in Korea |
| title_short | Low Iodine Diet for Preparation for Radioactive Iodine Therapy in Differentiated Thyroid Carcinoma in Korea |
| title_sort | low iodine diet for preparation for radioactive iodine therapy in differentiated thyroid carcinoma in korea |
| topic | Radioactive iodine Iodine Low iodine diet Urinary iodine concentration Urinary iodine excretion |
| url | http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-28-157.pdf |
| work_keys_str_mv | AT jaehoonchung lowiodinedietforpreparationforradioactiveiodinetherapyindifferentiatedthyroidcarcinomainkorea |