Could Azithromycin Be Part of Pseudomonas aeruginosa Acute Pneumonia Treatment?

Could Azithromycin Be Part of Pseudomonas aeruginosa Acute Pneumonia Treatment?

Azithromycin (AZM) is a 15-membered-ring macrolide that presents a broad-spectrum antimicrobial activity against Gram-positive bacteria and atypical microorganisms but suffers from a poor diffusion across the outer-membrane of Gram-negative bacilli, including Pseudomonas aeruginosa (PA). However, AZ...

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Bibliographic Details
Main Authors: Anne-Gaëlle Leroy, Jocelyne Caillon, Nathalie Caroff, Alexis Broquet, Stéphane Corvec, Karim Asehnoune, Antoine Roquilly, Lise Crémet
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Microbiology
Subjects:
macrolide
Pseudomonas aeruginosa
adjunctive therapy
critically ill patients
acute pulmonary infections
immunomodulation
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.642541/full

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