Land-locked mammalian Golgi reveals cargo transport between stable cisternae

The different composition of Golgi cisternae gave rise to two different models for intra-Golgi traffic: one where stable cisternae communicate via vesicles and another one where cisternae biochemically mature to ensure anterograde transport. Here, the authors provide evidence in support of the stabl...

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Main Authors: Myun Hwa Dunlop, Andreas M. Ernst, Lena K. Schroeder, Derek K. Toomre, Grégory Lavieu, James E. Rothman
Format: Article
Language:English
Published: Nature Portfolio 2017-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00570-z
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author Myun Hwa Dunlop
Andreas M. Ernst
Lena K. Schroeder
Derek K. Toomre
Grégory Lavieu
James E. Rothman
author_facet Myun Hwa Dunlop
Andreas M. Ernst
Lena K. Schroeder
Derek K. Toomre
Grégory Lavieu
James E. Rothman
author_sort Myun Hwa Dunlop
collection DOAJ
description The different composition of Golgi cisternae gave rise to two different models for intra-Golgi traffic: one where stable cisternae communicate via vesicles and another one where cisternae biochemically mature to ensure anterograde transport. Here, the authors provide evidence in support of the stable compartments model.
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spelling doaj.art-6f898b5c86a84ecca1c0327ce3e908d02022-12-21T23:38:32ZengNature PortfolioNature Communications2041-17232017-09-018111410.1038/s41467-017-00570-zLand-locked mammalian Golgi reveals cargo transport between stable cisternaeMyun Hwa Dunlop0Andreas M. Ernst1Lena K. Schroeder2Derek K. Toomre3Grégory Lavieu4James E. Rothman5Department of Cell Biology, Yale School of MedicineDepartment of Cell Biology, Yale School of MedicineDepartment of Cell Biology, Yale School of MedicineDepartment of Cell Biology, Yale School of MedicineDepartment of Cell Biology, Yale School of MedicineDepartment of Cell Biology, Yale School of MedicineThe different composition of Golgi cisternae gave rise to two different models for intra-Golgi traffic: one where stable cisternae communicate via vesicles and another one where cisternae biochemically mature to ensure anterograde transport. Here, the authors provide evidence in support of the stable compartments model.https://doi.org/10.1038/s41467-017-00570-z
spellingShingle Myun Hwa Dunlop
Andreas M. Ernst
Lena K. Schroeder
Derek K. Toomre
Grégory Lavieu
James E. Rothman
Land-locked mammalian Golgi reveals cargo transport between stable cisternae
Nature Communications
title Land-locked mammalian Golgi reveals cargo transport between stable cisternae
title_full Land-locked mammalian Golgi reveals cargo transport between stable cisternae
title_fullStr Land-locked mammalian Golgi reveals cargo transport between stable cisternae
title_full_unstemmed Land-locked mammalian Golgi reveals cargo transport between stable cisternae
title_short Land-locked mammalian Golgi reveals cargo transport between stable cisternae
title_sort land locked mammalian golgi reveals cargo transport between stable cisternae
url https://doi.org/10.1038/s41467-017-00570-z
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