Mechanized lymphatic drainage in acute decompensated heart failure. A study on a hydrodynamic test bench
Objective: to investigate the effectiveness of a new mechanized lymphatic drainage method in acute decompensated heart failure (ADHF) modeling through local reduction in venous pressure in the site of lymphatic drainage from the thoracic duct.Materials and methods. Main components of the device are...
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| Format: | Article |
| Language: | Russian |
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Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
2022-12-01
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| Series: | Vestnik Transplantologii i Iskusstvennyh Organov |
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| Online Access: | https://journal.transpl.ru/vtio/article/view/1568 |
| _version_ | 1797871861510438912 |
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| author | A. S. Buchnev G. P. Itkin A. A. Drobyshev A. P. Kuleshov O. Yu. Esipova A. I. Syrbu |
| author_facet | A. S. Buchnev G. P. Itkin A. A. Drobyshev A. P. Kuleshov O. Yu. Esipova A. I. Syrbu |
| author_sort | A. S. Buchnev |
| collection | DOAJ |
| description | Objective: to investigate the effectiveness of a new mechanized lymphatic drainage method in acute decompensated heart failure (ADHF) modeling through local reduction in venous pressure in the site of lymphatic drainage from the thoracic duct.Materials and methods. Main components of the device are a catheter with built-in inlet and outlet mechanical valves designed for insertion into the left brachiocephalic vein through the left internal jugular vein. It comes with an extracorporeal drive system made as a valveless pulsator pump with a 10 ml shock discharge and a controller ensuring preset frequency and pressure/rarefaction duty cycle. The operating principle of the device is based on local reduction of venous pressure in the site of lymphatic drainage from the thoracic duct (in the junction of the left internal jugular and subclavian veins).Results. When modeling hydrodynamics under ADHF conditions on a hydrodynamic test bench, the upper venous flow through the left brachiocephalic vein was 0.4 l/min, the pressure in the site of lymphatic drainage from the thoracic duct, was decreased from 20–25 mmHg to 0–5 mmHg due to operation of the mechanized drainage device with suction/injection phase duration ratio 0.2/0.8 and pulsator pump operating frequency from 30 to 60 beats/min. |
| first_indexed | 2024-04-10T00:50:43Z |
| format | Article |
| id | doaj.art-6f8da3c198a94cd49b4da5b87ed549fc |
| institution | Directory Open Access Journal |
| issn | 1995-1191 |
| language | Russian |
| last_indexed | 2024-04-10T00:50:43Z |
| publishDate | 2022-12-01 |
| publisher | Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov |
| record_format | Article |
| series | Vestnik Transplantologii i Iskusstvennyh Organov |
| spelling | doaj.art-6f8da3c198a94cd49b4da5b87ed549fc2023-03-13T10:37:29ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovVestnik Transplantologii i Iskusstvennyh Organov1995-11912022-12-01244545910.15825/1995-1191-2022-4-54-591146Mechanized lymphatic drainage in acute decompensated heart failure. A study on a hydrodynamic test benchA. S. Buchnev0G. P. Itkin1A. A. Drobyshev2A. P. Kuleshov3O. Yu. Esipova4A. I. Syrbu5Shumakov National Medical Research Center of Transplantology and Artificial OrgansShumakov National Medical Research Center of Transplantology and Artificial Organs; Moscow Institute of Physics and TechnologyShumakov National Medical Research Center of Transplantology and Artificial OrgansShumakov National Medical Research Center of Transplantology and Artificial OrgansShumakov National Medical Research Center of Transplantology and Artificial OrgansShumakov National Medical Research Center of Transplantology and Artificial OrgansObjective: to investigate the effectiveness of a new mechanized lymphatic drainage method in acute decompensated heart failure (ADHF) modeling through local reduction in venous pressure in the site of lymphatic drainage from the thoracic duct.Materials and methods. Main components of the device are a catheter with built-in inlet and outlet mechanical valves designed for insertion into the left brachiocephalic vein through the left internal jugular vein. It comes with an extracorporeal drive system made as a valveless pulsator pump with a 10 ml shock discharge and a controller ensuring preset frequency and pressure/rarefaction duty cycle. The operating principle of the device is based on local reduction of venous pressure in the site of lymphatic drainage from the thoracic duct (in the junction of the left internal jugular and subclavian veins).Results. When modeling hydrodynamics under ADHF conditions on a hydrodynamic test bench, the upper venous flow through the left brachiocephalic vein was 0.4 l/min, the pressure in the site of lymphatic drainage from the thoracic duct, was decreased from 20–25 mmHg to 0–5 mmHg due to operation of the mechanized drainage device with suction/injection phase duration ratio 0.2/0.8 and pulsator pump operating frequency from 30 to 60 beats/min.https://journal.transpl.ru/vtio/article/view/1568lymphatic systemthoracic ductheart failurelocal decrease in venous pressurecatheterpulsator pump |
| spellingShingle | A. S. Buchnev G. P. Itkin A. A. Drobyshev A. P. Kuleshov O. Yu. Esipova A. I. Syrbu Mechanized lymphatic drainage in acute decompensated heart failure. A study on a hydrodynamic test bench Vestnik Transplantologii i Iskusstvennyh Organov lymphatic system thoracic duct heart failure local decrease in venous pressure catheter pulsator pump |
| title | Mechanized lymphatic drainage in acute decompensated heart failure. A study on a hydrodynamic test bench |
| title_full | Mechanized lymphatic drainage in acute decompensated heart failure. A study on a hydrodynamic test bench |
| title_fullStr | Mechanized lymphatic drainage in acute decompensated heart failure. A study on a hydrodynamic test bench |
| title_full_unstemmed | Mechanized lymphatic drainage in acute decompensated heart failure. A study on a hydrodynamic test bench |
| title_short | Mechanized lymphatic drainage in acute decompensated heart failure. A study on a hydrodynamic test bench |
| title_sort | mechanized lymphatic drainage in acute decompensated heart failure a study on a hydrodynamic test bench |
| topic | lymphatic system thoracic duct heart failure local decrease in venous pressure catheter pulsator pump |
| url | https://journal.transpl.ru/vtio/article/view/1568 |
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