Dynamic loading, matrix maintenance and cell injection therapy of human intervertebral discs cultured in a bioreactor

Low back pain originating from intervertebral disc (IVD) degeneration affects the quality of life for millions of people, and it is a major contributor to global healthcare costs. Long-term culture of intact IVDs is necessary to develop ex vivo models of human IVD degeneration and repair, where the...

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Bibliographic Details
Main Authors: DH Rosenzweig, R Gawri, J Moir, L Beckman, D Eglin, T Steffen, PJ Roughley, JA Ouellet, L Haglund
Format: Article
Language:English
Published: Forum Multimedia Publishing LLC 2016-01-01
Series:European Cells & Materials
Subjects:
Online Access:http://www.ecmjournal.org/papers/vol031/pdf/v031a03.pdf