Longitudinal Variations in Antibody Responses against SARS-CoV-2 Spike Epitopes upon Serial Vaccinations

Longitudinal Variations in Antibody Responses against SARS-CoV-2 Spike Epitopes upon Serial Vaccinations

The COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) impacted healthcare, the workforce, and worldwide socioeconomics. Multi-dose mono- or bivalent mRNA vaccine regimens have shown high efficacy in protection against SARS-CoV-2 and its emerging variants wi...

Full description

Bibliographic Details
Main Authors:	Dicle Yalcin, Sydney J. Bennett, Jared Sheehan, Amber J. Trauth, For Yue Tso, John T. West, Michael E. Hagensee, Alistair J. Ramsay, Charles Wood
Format:	Article
Language:	English
Published:	MDPI AG 2023-04-01
Series:	International Journal of Molecular Sciences
Subjects:	SARS-CoV-2 mRNA vaccine VirScan PhIP-Seq spike epitope map
Online Access:	https://www.mdpi.com/1422-0067/24/8/7292

Similar Items

Applications of VirScan to broad serological profiling of bat reservoirs for emerging zoonoses
by: Emily Cornelius Ruhs, et al.
Published: (2023-09-01)

Deconvoluting virome-wide antibody epitope reactivity profiles
by: Daniel R. Monaco, et al.
Published: (2022-01-01)

Immunogenic epitope scanning in bacteriolytic enzymes Pal and Cpl-1 and engineering Pal to escape antibody responses
by: Marek Adam Harhala, et al.
Published: (2023-09-01)

Viral Epitope Scanning Reveals Correlation between Seasonal HCoVs and SARS-CoV-2 Antibody Responses among Cancer and Non-Cancer Patients
by: Salum J. Lidenge, et al.
Published: (2024-03-01)

Comprehensive profiling of the human viral exposome in households containing an at‐risk child with mitochondrial disease during the 2020–2021 COVID‐19 pandemic
by: Eliza M. Gordon‐Lipkin, et al.
Published: (2022-11-01)

Primary oxidative phosphorylation defects lead to perturbations in the human B cell repertoire
by: Eliza M. Gordon-Lipkin, et al.
Published: (2023-07-01)

Effect of Immersion Time of Chicken Breast in Potato Starch Coating Containing Lysine on PhIP Levels
by: Parastou Farshi, et al.
Published: (2024-01-01)

A Case of Persistent Human Pegivirus Infection in Two Separate Pregnancies of a Woman
by: Mathieu Garand, et al.
Published: (2022-09-01)

HIV Antibody Profiles in HIV Controllers and Persons With Treatment-Induced Viral Suppression
by: Kai Kammers, et al.
Published: (2021-08-01)

Bioinformatic Analysis Identified Hub Genes Associated with Heterocyclic Amines Induced Cytotoxicity of Peripheral Blood Mononuclear Cells
by: Xinyang Li, et al.
Published: (2021-11-01)

Inna Pavlovna Gavrilyuk (1939–2022): (in memory of the scientist)
by: A. V. Konarev
Published: (2022-06-01)

Effect of acrolein, a lipid oxidation product, on the formation of the heterocyclic aromatic amine 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in model systems and roasted tilapia fish patties
by: Meilin Jing, et al.
Published: (2022-06-01)

Identification of a novel B-cell epitope in the spike protein of porcine epidemic diarrhea virus
by: Ning Kong, et al.
Published: (2020-04-01)

Immunoinformatics Study: Multi-Epitope Based Vaccine Design from SARS-CoV-2 Spike Glycoprotein
by: Ramadhita Umitaibatin, et al.
Published: (2023-02-01)

The evaluation of catechins reducing heterocyclic aromatic amine formation: Structure-activity relationship and mechanism speculation
by: Ruiwei Xie, et al.
Published: (2024-01-01)

Comirnaty-Elicited and Convalescent Sera Recognize Different Spike Epitopes
by: Sascha Hein, et al.
Published: (2021-12-01)

Identification of novel, clinically correlated autoantigens in the monogenic autoimmune syndrome APS1 by proteome-wide PhIP-Seq
by: Sara E Vazquez, et al.
Published: (2020-05-01)

Autoantibody discovery across monogenic, acquired, and COVID-19-associated autoimmunity with scalable PhIP-seq
by: Sara E Vazquez, et al.
Published: (2022-10-01)

Establishment of Novel Genotoxicity Assay System Using Murine Normal Epithelial Tissue-Derived Organoids
by: Masami Komiya, et al.
Published: (2021-11-01)

Identification of three conserved linear B cell epitopes on the SARS-CoV-2 spike protein
by: Aiping Wang, et al.
Published: (2022-12-01)

Revealing Novel-Strain-Specific and Shared Epitopes of Infectious Bronchitis Virus Spike Glycoprotein Using Chemical Linkage of Peptides onto Scaffolds Precision Epitope Mapping
by: Samantha Sives, et al.
Published: (2023-11-01)

Colon Transcriptomics Reveals Sex-Dependent Metabolic Signatures in Response to 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine Treatment in C57BL/6N Mice
by: Jeong Hoon Pan, et al.
Published: (2020-09-01)

Phage ImmunoPrecipitation Sequencing (PhIP-Seq): The Promise of High Throughput Serology
by: Charles Kevin Tiu, et al.
Published: (2022-05-01)

Grape seed extract ameliorates PhIP-induced colonic injury by modulating gut microbiota, lipid metabolism, and NF-κB signaling pathway in rats
by: Xiuli Zhao, et al.
Published: (2021-03-01)

Spike protein-based epitopes predicted against SARS-CoV-2 through literature mining
by: Wendong Li, et al.
Published: (2020-12-01)

Dynamics of Serum-Neutralizing Antibody Responses in Vaccinees through Multiple Doses of the BNT162b2 Vaccine
by: Jared Sheehan, et al.
Published: (2023-11-01)

Identification of Closed Linear Epitopes in S1-RBD and S2-HR1/2 of SARS-CoV-2 Spike Protein Able to Induce Neutralizing Abs
by: Yoshihiro Watanabe, et al.
Published: (2023-01-01)

PhIP-Seq Reveals Autoantibodies for Ubiquitously Expressed Antigens in Viral Myocarditis
by: Mahima T. Rasquinha, et al.
Published: (2022-07-01)

Inflammation and Atrophy Precede Prostatic Neoplasia in a PhIP-Induced Rat Model
by: Alexander D. Borowsky, et al.
Published: (2006-09-01)

Computational design of SARS-CoV-2 spike glycoproteins to increase immunogenicity by T cell epitope engineering
by: Edison Ong, et al.
Published: (2021-01-01)

Omicron-included mutation-induced changes in epitopes of SARS-CoV-2 spike protein and effectiveness assessments of current antibodies
by: Du Guo, et al.
Published: (2022-04-01)

Variations in SARS-CoV-2 Spike Protein Cell Epitopes and Glycosylation Profiles During Global Transmission Course of COVID-19
by: Wenxin Xu, et al.
Published: (2020-09-01)

Agrobacterium VirD2-Binding Protein Is Involved in Tumorigenesis and Redundantly Encoded in Conjugative Transfer Gene Clusters
by: Minliang Guo, et al.
Published: (2007-10-01)

Heterocyclic Amine Formation in Grilled Chicken Depending on Body Parts and Treatment Conditions
by: Dániel Pleva, et al.
Published: (2020-03-01)

Three Specific Potential Epitopes That Could Be Recognized by T Cells of Convalescent COVID-19 Patients Were Identified From Spike Protein
by: Yunwen Zhang, et al.
Published: (2022-01-01)

Identification of B-Cell Epitopes for Eliciting Neutralizing Antibodies against the SARS-CoV-2 Spike Protein through Bioinformatics and Monoclonal Antibody Targeting
by: Hui Xuan Lim, et al.
Published: (2022-04-01)

A Novel Conserved Linear Neutralizing Epitope on the Receptor-Binding Domain of the SARS-CoV-2 Spike Protein
by: Rong-Hong Hua, et al.
Published: (2023-08-01)

A newly identified linear epitope on non-RBD region of SARS-CoV-2 spike protein improves the serological detection rate of COVID-19 patients
by: Yunwen Zhang, et al.
Published: (2021-06-01)

Methodical approach for determination of the heterocyclic aromatic amines in meat products using HPLC–MS/MS
by: D. A. Utyanov, et al.
Published: (2021-07-01)

On the history of VIR foundation
by: V. K. Shumny, et al.
Published: (2019-10-01)