Nutrient-sensing growth hormone secretagogue receptor in macrophage programming and meta-inflammation

Nutrient-sensing growth hormone secretagogue receptor in macrophage programming and meta-inflammation

Objective: Obesity-associated chronic inflammation, aka meta-inflammation, is a key pathogenic driver for obesity-associated comorbidity. Growth hormone secretagogue receptor (GHSR) is known to mediate the effects of nutrient-sensing hormone ghrelin in food intake and fat deposition. We previously r...

Full description

Bibliographic Details
Main Authors:	Da Mi Kim, Jong Han Lee, Quan Pan, Hye Won Han, Zheng Shen, Sahar Eshghjoo, Chia-Shan Wu, Wanbao Yang, Ji Yeon Noh, David W. Threadgill, Shaodong Guo, Gus Wright, Robert Alaniz, Yuxiang Sun
Format:	Article
Language:	English
Published:	Elsevier 2024-01-01
Series:	Molecular Metabolism
Subjects:	Macrophage GHSR Meta-inflammation Macrophage polarization Insulin resistance Obesity
Online Access:	http://www.sciencedirect.com/science/article/pii/S2212877823001862

Similar Items

Nutrient-Sensing Ghrelin Receptor in Macrophages Modulates Bisphenol A-Induced Intestinal Inflammation in Mice
by: Xiangcang Ye, et al.
Published: (2023-07-01)

Deletion of Growth Hormone Secretagogue Receptor in Kisspeptin Neurons in Female Mice Blocks Diet-Induced Obesity
by: Kristie Conde, et al.
Published: (2022-09-01)

Exploring Metabolic Pathways of Anamorelin, a Selective Agonist of the Growth Hormone Secretagogue Receptor, via Molecular Networking
by: Young Beom Kwak, et al.
Published: (2023-11-01)

Macrophage Polarization in Atherosclerosis
by: Sahar Eshghjoo, et al.
Published: (2022-04-01)

Establishment of a Cell Line Stably Expressing the Growth Hormone Secretagogue Receptor to Identify Crocin as a Ghrelin Agonist
by: Chia-Hao Wang, et al.
Published: (2022-12-01)

LEAP2 deletion in mice enhances ghrelin's actions as an orexigen and growth hormone secretagogue
by: Kripa Shankar, et al.
Published: (2021-11-01)

Exploring the Relationship Between Growth Hormone Secretagogue Receptor (GHSR) Gene and Body Proportions in Bangkok Chickens: Insights from DNA Sequencing and Hin6I Enzyme-Restricted PCR-RFLP Analysis
by: Gayuh Syaikhullah, et al.
Published: (2024-04-01)

Neuronal ablation of GHSR mitigates diet-induced depression and memory impairment via AMPK-autophagy signaling-mediated inflammation
by: Hongying Wang, et al.
Published: (2024-02-01)

Microbiota-Mediated Immune Regulation in Atherosclerosis
by: Sahar Eshghjoo, et al.
Published: (2021-01-01)

Disrupting the ghrelin-growth hormone axis limits ghrelin's orexigenic but not glucoregulatory actions
by: Deepali Gupta, et al.
Published: (2021-11-01)

The role of ghrelin-responsive mediobasal hypothalamic neurons in mediating feeding responses to fasting
by: Bharath K. Mani, et al.
Published: (2017-08-01)

Ghrelin and Cancer: Examining the Roles of the Ghrelin Axis in Tumor Growth and Progression
by: Anuhya S. Kotta, et al.
Published: (2022-03-01)

Research Trends of Macrophage Polarization: A Bibliometric Analysis
by: Han Gao, et al.
Published: (2018-01-01)

How mouse macrophages sense what is going on
by: Klaus eLey, et al.
Published: (2016-06-01)

The role of macrophage in atherosclerosis: An overview
by: İbrahim Halil Damar, et al.
Published: (2020-12-01)

Association Analysis of the Leptin and Ghrelin Receptor Gene Polymorphism in the Human with BMI
by: Zuzana Lieskovská, et al.
Published: (2023-11-01)

Origins and diversity of macrophages in health and disease
by: Gopalkrishna Sreejit, et al.
Published: (2020-01-01)

Macrophage Polarization and Osteoporosis: A Review
by: Joseph Muñoz, et al.
Published: (2020-09-01)

Monocytic Ontogeny of Regenerated Macrophages Characterizes the Mesotheliomagenic Responses to Carbon Nanotubes
by: Micaela Orsi, et al.
Published: (2021-06-01)

Regulation of metabolic and transcriptional responses by the thyroid hormone in cellular models of murine macrophages
by: Irene López-Mateo, et al.
Published: (2022-07-01)

Macrophage Rewiring by Nutrient Associated PI3K Dependent Pathways
by: Omar Sharif, et al.
Published: (2019-08-01)

The role of macrophage subtypes and exosomes in immunomodulation
by: Abdulwahab Teflischi Gharavi, et al.
Published: (2022-10-01)

Editorial: Transcriptional regulation of macrophage function
by: Zsolt Czimmerer, et al.
Published: (2023-11-01)

Functional Phenotypes of Intraplaque Macrophages and Their Distinct Roles in Atherosclerosis Development and Atheroinflammation
by: Nataliya V. Mushenkova, et al.
Published: (2022-02-01)

Treponema pallidum induces the polarization of macrophages via macrophage-derived exosomes
by: Chunchan ZHENG, et al.
Published: (2022-10-01)

Ghrelin mediated regulation of neurosynaptic transmitters in depressive disorders
by: Milind V. Masule, et al.
Published: (2022-01-01)

Different forms of ghrelin exhibit distinct biological roles in tilapia
by: Larry eRiley
Published: (2013-09-01)

GSK3β Inhibition Prevents Macrophage Reprogramming by High-Dose Methotrexate
by: Israel Ríos, et al.
Published: (2022-11-01)

Of Mice and Men: Arginine metabolism in macrophages
by: Anita C Thomas, et al.
Published: (2014-10-01)

Functional aspects, phenotypic heterogeneity, and tissue immune response of macrophages in infectious diseases
by: de Sousa JR, et al.
Published: (2019-08-01)

Investigating the Effects of Sex Hormones on Macrophage Polarization
by: Sophie Enright, et al.
Published: (2024-01-01)

Metabolic Hormones Modulate Macrophage Inflammatory Responses
by: Matthew J. Batty, et al.
Published: (2021-09-01)

MicroRNA: role in macrophage polarization and the pathogenesis of the liver fibrosis
by: Wen Yu, et al.
Published: (2023-04-01)

Tumour-associated macrophages: versatile players in the tumour microenvironment
by: Zoey Zeyuan Ji, et al.
Published: (2023-10-01)

Meta-Analysis of in vitro-Differentiated Macrophages Identifies Transcriptomic Signatures That Classify Disease Macrophages in vivo
by: Hung-Jen Chen, et al.
Published: (2019-12-01)

Studies on metabolism in macrophages
by: Newsholme, P, et al.
Published: (1987)

Macrophage polarization in sarcoidosis
by: I. E. Malysheva, et al.
Published: (2021-03-01)

High Content Image Analysis as a Tool to Morphologically Distinguish Macrophage Activation and Determine Its Importance for Foamy Alveolar Macrophage Responses
by: Ewelina Hoffman, et al.
Published: (2021-09-01)

Role of Distinct Macrophage Populations in the Development of Heart Failure in Macrophage Activation Syndrome
by: Jakub Kuna, et al.
Published: (2022-02-01)

Mitochondrial DNA on Tumor-Associated Macrophages Polarization and Immunity
by: Yaxin Guo, et al.
Published: (2022-03-01)