Psychosocial aspects and life project disruption in young women diagnosed with metastatic hormone-sensitive HER2-negative breast cancer
Metastatic breast cancer (MBC) diagnosis in young women negatively impacts on quality of life (QoL) and daily activities, disrupting their life project and forcing them to face new psychosocial challenges. The recently published results on the improvement of the overall survival of pre- or perimenop...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-10-01
|
| Series: | Breast |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0960977620301375 |
| _version_ | 1819069816805261312 |
|---|---|
| author | Mireia Margelí Vila Sonia del Barco Berron Miguel Gil-Gil Cristian Ochoa-Arnedo Rafael Villanueva Vázquez |
| author_facet | Mireia Margelí Vila Sonia del Barco Berron Miguel Gil-Gil Cristian Ochoa-Arnedo Rafael Villanueva Vázquez |
| author_sort | Mireia Margelí Vila |
| collection | DOAJ |
| description | Metastatic breast cancer (MBC) diagnosis in young women negatively impacts on quality of life (QoL) and daily activities, disrupting their life project and forcing them to face new psychosocial challenges. The recently published results on the improvement of the overall survival of pre- or perimenopausal women with hormone-receptor-positive, HER2-negative MBC treated with CDK4/6 inhibitors plus endocrine therapy, while preserving, and in some items improving their QoL, will change the landscape of the management of this patient population. Their extended survival and potential improvement in QoL will, therefore, modify their specific needs in terms of psychosocial support.The complexity of the care of young women with MBC is described herein, based on an extensive literature review. Further research about the specific psychosocial requirements of these women and a new multidisciplinary holistic approach is paramount to properly address their concerns and preferences. The communication with and support of their partners, parents and children is an important factor affecting the QoL of these patients. Altogether, a multidisciplinary care, open communication and personalized support is required to address the psychosocial implications of the new prognostic expectations on these patients with the incorporation of new targeted therapies. |
| first_indexed | 2024-12-21T16:56:04Z |
| format | Article |
| id | doaj.art-6f90251dcae54c65b87e32e265901995 |
| institution | Directory Open Access Journal |
| issn | 1532-3080 |
| language | English |
| last_indexed | 2024-12-21T16:56:04Z |
| publishDate | 2020-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Breast |
| spelling | doaj.art-6f90251dcae54c65b87e32e2659019952022-12-21T18:56:45ZengElsevierBreast1532-30802020-10-01534450Psychosocial aspects and life project disruption in young women diagnosed with metastatic hormone-sensitive HER2-negative breast cancerMireia Margelí Vila0Sonia del Barco Berron1Miguel Gil-Gil2Cristian Ochoa-Arnedo3Rafael Villanueva Vázquez4B-ARGO Group, Institut Català D’Oncologia, Medical Oncology Service, Hospital Germans Trias i Pujol, Badalona, SpainBreast Cancer Unit. Institut Català D’Oncologia, Hospital Universitari Josep Trueta, Girona, SpainMedical Oncology Unit. Institut Català D’Oncologia, L’Hospitalet de Llobregat, Barcelona, Spain; Institut D’Investigació Biomèdica de Bellvitge - IDIBELL, L’Hospitalet de Llobregat, Barcelona, SpainPsycho-Oncology Unit. Institut Català D’Oncologia, L’Hospitalet de Llobregat, Barcelona, Spain; Clinical Psychology and Psychobiology Department, Universitat de Barcelona, Spain; Institut D’Investigació Biomèdica de Bellvitge - IDIBELL, L’Hospitalet de Llobregat, Barcelona, SpainMedical Oncology Unit. Institut Català D’Oncologia, L’Hospitalet de Llobregat, Barcelona, Spain; Breast Cancer Unit. Institut Català D’Oncologia, Hospital Moisès Broggi. Sant Joan Despí, Barcelona, Spain; Corresponding author. Institut Català d’Oncologia Hospital Moisès Broggi, Sant Joan Despí, Barcelona, Spain.Metastatic breast cancer (MBC) diagnosis in young women negatively impacts on quality of life (QoL) and daily activities, disrupting their life project and forcing them to face new psychosocial challenges. The recently published results on the improvement of the overall survival of pre- or perimenopausal women with hormone-receptor-positive, HER2-negative MBC treated with CDK4/6 inhibitors plus endocrine therapy, while preserving, and in some items improving their QoL, will change the landscape of the management of this patient population. Their extended survival and potential improvement in QoL will, therefore, modify their specific needs in terms of psychosocial support.The complexity of the care of young women with MBC is described herein, based on an extensive literature review. Further research about the specific psychosocial requirements of these women and a new multidisciplinary holistic approach is paramount to properly address their concerns and preferences. The communication with and support of their partners, parents and children is an important factor affecting the QoL of these patients. Altogether, a multidisciplinary care, open communication and personalized support is required to address the psychosocial implications of the new prognostic expectations on these patients with the incorporation of new targeted therapies.http://www.sciencedirect.com/science/article/pii/S0960977620301375Psycho-oncologyMetastatic breast cancerPremenopausal womenCDK4/6 inhibitorQuality of lifeHormone-receptor-positive /HER2-Negative |
| spellingShingle | Mireia Margelí Vila Sonia del Barco Berron Miguel Gil-Gil Cristian Ochoa-Arnedo Rafael Villanueva Vázquez Psychosocial aspects and life project disruption in young women diagnosed with metastatic hormone-sensitive HER2-negative breast cancer Breast Psycho-oncology Metastatic breast cancer Premenopausal women CDK4/6 inhibitor Quality of life Hormone-receptor-positive /HER2-Negative |
| title | Psychosocial aspects and life project disruption in young women diagnosed with metastatic hormone-sensitive HER2-negative breast cancer |
| title_full | Psychosocial aspects and life project disruption in young women diagnosed with metastatic hormone-sensitive HER2-negative breast cancer |
| title_fullStr | Psychosocial aspects and life project disruption in young women diagnosed with metastatic hormone-sensitive HER2-negative breast cancer |
| title_full_unstemmed | Psychosocial aspects and life project disruption in young women diagnosed with metastatic hormone-sensitive HER2-negative breast cancer |
| title_short | Psychosocial aspects and life project disruption in young women diagnosed with metastatic hormone-sensitive HER2-negative breast cancer |
| title_sort | psychosocial aspects and life project disruption in young women diagnosed with metastatic hormone sensitive her2 negative breast cancer |
| topic | Psycho-oncology Metastatic breast cancer Premenopausal women CDK4/6 inhibitor Quality of life Hormone-receptor-positive /HER2-Negative |
| url | http://www.sciencedirect.com/science/article/pii/S0960977620301375 |
| work_keys_str_mv | AT mireiamargelivila psychosocialaspectsandlifeprojectdisruptioninyoungwomendiagnosedwithmetastatichormonesensitiveher2negativebreastcancer AT soniadelbarcoberron psychosocialaspectsandlifeprojectdisruptioninyoungwomendiagnosedwithmetastatichormonesensitiveher2negativebreastcancer AT miguelgilgil psychosocialaspectsandlifeprojectdisruptioninyoungwomendiagnosedwithmetastatichormonesensitiveher2negativebreastcancer AT cristianochoaarnedo psychosocialaspectsandlifeprojectdisruptioninyoungwomendiagnosedwithmetastatichormonesensitiveher2negativebreastcancer AT rafaelvillanuevavazquez psychosocialaspectsandlifeprojectdisruptioninyoungwomendiagnosedwithmetastatichormonesensitiveher2negativebreastcancer |