Design, synthesis and biological evaluation of novel benzodioxole derivatives as COX inhibitors and cytotoxic agents
Abstract Non-steroidal anti-inflammatory drugs are among the most used drugs. They are competitive inhibitors of cyclooxygenase (COX). Twelve novel compounds (aryl acetate and aryl acetic acid groups) were synthesized in this work in order to identify which one was the most potent and which group wa...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2020-09-01
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| Series: | BMC Chemistry |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13065-020-00706-1 |