In vivo blockade of 5HT3 receptors in the infralimbic medial prefrontal cortex enhances fear extinction in a rat model of PTSD

In vivo blockade of 5HT3 receptors in the infralimbic medial prefrontal cortex enhances fear extinction in a rat model of PTSD

Objective(s): Treatments that reverse deficits in fear extinction are promising for the management of post-traumatic stress disorder (PTSD). 5-Hydroxytryptamine type 3 (5-HT3) receptor is involved in the extinction of fear memories. The present work aims to investigate the role of 5HT3 receptors in...

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Bibliographic Details
Main Authors:	Ahmad Mohammadi-Farani, Mahdi Taghadosi, Sara Raziee, Zahra Samimi
Format:	Article
Language:	English
Published:	Mashhad University of Medical Sciences 2021-06-01
Series:	Iranian Journal of Basic Medical Sciences
Subjects:	fear extinction infralimbic medial prefrontal cortex ptsd single prolonged stress 5ht3 receptor
Online Access:	https://ijbms.mums.ac.ir/article_17979_3918f1f27287160626ec1f96d55d3c5a.pdf

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