Synthesis, Antiproliferative Activity and In Silico Studies of Chalcones Derived From 4-(Imidazole-1-yl)Acetophenone

Synthesis, Antiproliferative Activity and In Silico Studies of Chalcones Derived From 4-(Imidazole-1-yl)Acetophenone

In this study, the synthesis of chalcone compounds (1-11) derived from 4-(imidazol-1-yl)acetophenone and the structure determination of these compounds by various spectroscopic methods were carried out. The anticancer activities of compounds 1-11 were examined against HeLa and PC-3 cancer cells at f...

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Bibliographic Details
Main Authors: Bedriye Seda KURŞUN AKTAR, Abdulraheem Mustafa ALKARABASH, Ayşe ŞAHİN YAĞLIOĞLU, Emine Elçin ORUÇ-EMRE
Format: Article
Language:English
Published: Turkish Chemical Society 2023-08-01
Series:Journal of the Turkish Chemical Society, Section A: Chemistry
Subjects:
adme
antiproliferative activity
hela cell line
in silico.
pc-3 cell line
Online Access:https://dergipark.org.tr/tr/pub/jotcsa/issue/78393/1313595

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