Intralenticular Ozurdex® – One Year Later

Reported here is a case of intralenticular sustained-release dexamethasone implant (Ozurdex®, Allergan, Irvine, CA, USA) present for 1 year with effective treatment of refractory diabetic macular edema without rapid cataract formation. The crystalline lens remained stable for 12 months on exam despi...

Full description

Bibliographic Details
Main Authors: Kathleen A. Regan, Charles R. Blake, Zachary L. Lukowski, Siva S.R. Iyer
Format: Article
Language:English
Published: Karger Publishers 2017-12-01
Series:Case Reports in Ophthalmology
Subjects:
Online Access:https://www.karger.com/Article/FullText/485318
_version_ 1818886725430149120
author Kathleen A. Regan
Charles R. Blake
Zachary L. Lukowski
Siva S.R. Iyer
author_facet Kathleen A. Regan
Charles R. Blake
Zachary L. Lukowski
Siva S.R. Iyer
author_sort Kathleen A. Regan
collection DOAJ
description Reported here is a case of intralenticular sustained-release dexamethasone implant (Ozurdex®, Allergan, Irvine, CA, USA) present for 1 year with effective treatment of refractory diabetic macular edema without rapid cataract formation. The crystalline lens remained stable for 12 months on exam despite the presence of the steroid-secreting foreign body. The diabetic macular edema resolved on exam and on optical coherence tomography. After 1 year, cataract extraction was uneventfully performed by phacoemulsification for a mild decline in visual acuity. Macular edema remains resolved 2 months following cataract removal. This is the longest reported period of observation of intralenticular Ozurdex in the literature. Ozurdex remains effective despite intralenticular location, and it can have minimal effects on cataract progression.
first_indexed 2024-12-19T16:25:54Z
format Article
id doaj.art-6f99b7041c1e49059cc49158c116e3e3
institution Directory Open Access Journal
issn 1663-2699
language English
last_indexed 2024-12-19T16:25:54Z
publishDate 2017-12-01
publisher Karger Publishers
record_format Article
series Case Reports in Ophthalmology
spelling doaj.art-6f99b7041c1e49059cc49158c116e3e32022-12-21T20:14:20ZengKarger PublishersCase Reports in Ophthalmology1663-26992017-12-018359059410.1159/000485318485318Intralenticular Ozurdex® – One Year LaterKathleen A. ReganCharles R. BlakeZachary L. LukowskiSiva S.R. IyerReported here is a case of intralenticular sustained-release dexamethasone implant (Ozurdex®, Allergan, Irvine, CA, USA) present for 1 year with effective treatment of refractory diabetic macular edema without rapid cataract formation. The crystalline lens remained stable for 12 months on exam despite the presence of the steroid-secreting foreign body. The diabetic macular edema resolved on exam and on optical coherence tomography. After 1 year, cataract extraction was uneventfully performed by phacoemulsification for a mild decline in visual acuity. Macular edema remains resolved 2 months following cataract removal. This is the longest reported period of observation of intralenticular Ozurdex in the literature. Ozurdex remains effective despite intralenticular location, and it can have minimal effects on cataract progression.https://www.karger.com/Article/FullText/485318Intralenticular dexamethasone implantation (Ozurdex®)Diabetic macular edemaNuclear sclerotic cataract
spellingShingle Kathleen A. Regan
Charles R. Blake
Zachary L. Lukowski
Siva S.R. Iyer
Intralenticular Ozurdex® – One Year Later
Case Reports in Ophthalmology
Intralenticular dexamethasone implantation (Ozurdex®)
Diabetic macular edema
Nuclear sclerotic cataract
title Intralenticular Ozurdex® – One Year Later
title_full Intralenticular Ozurdex® – One Year Later
title_fullStr Intralenticular Ozurdex® – One Year Later
title_full_unstemmed Intralenticular Ozurdex® – One Year Later
title_short Intralenticular Ozurdex® – One Year Later
title_sort intralenticular ozurdex r one year later
topic Intralenticular dexamethasone implantation (Ozurdex®)
Diabetic macular edema
Nuclear sclerotic cataract
url https://www.karger.com/Article/FullText/485318
work_keys_str_mv AT kathleenaregan intralenticularozurdexoneyearlater
AT charlesrblake intralenticularozurdexoneyearlater
AT zacharyllukowski intralenticularozurdexoneyearlater
AT sivasriyer intralenticularozurdexoneyearlater