The clinical characteristics of anemia in native adults living at different altitudes of the Tibetan Plateau
Abstract To provide evidence-based medicine references for formulating prevention and control policies in plateau areas, we explore the characteristics of anemia patients in Tibet (the plateau areas of China), especially those located at an altitude above 4500 m. We collected clinical data from 379...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-02-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-26868-7 |
| _version_ | 1797864910897545216 |
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| author | Jie Fang Ran Li Dongdong Ye Liang Chen Luo Bu Zhuo Ma Yinyin Zhang Jun Zhu Xiaodong Gao Pengpeng Xu Yu Zheng Xiaoyang Li Jianhua You Chuanhe Jiang Kai Qing Fei Yue Junmin Li Pu Bu Wang Dui Kai Xue |
| author_facet | Jie Fang Ran Li Dongdong Ye Liang Chen Luo Bu Zhuo Ma Yinyin Zhang Jun Zhu Xiaodong Gao Pengpeng Xu Yu Zheng Xiaoyang Li Jianhua You Chuanhe Jiang Kai Qing Fei Yue Junmin Li Pu Bu Wang Dui Kai Xue |
| author_sort | Jie Fang |
| collection | DOAJ |
| description | Abstract To provide evidence-based medicine references for formulating prevention and control policies in plateau areas, we explore the characteristics of anemia patients in Tibet (the plateau areas of China), especially those located at an altitude above 4500 m. We collected clinical data from 379 Tibetan anemia patients over the age of 18 years. We found those female patients accounted for the majority of Tibetan anemia patients. Almost half of the anemia patients aged from 28 to 47 years. The percentage of severe anemia and extremely severe anemia was 45.4% and 2.4%, respectively. 88.7% of patients are engaged in agriculture and animal husbandry, and 81.5% of patients just graduated from primary school or below. The most common causes of anemia were nutritional anemia, especially iron-deficiency anemia. At high-altitude localities, folic acid-deficiency anemia needs more attention. Overall, this study showed that altitude influences the incidence, severity, and cause of anemia. Peasants and herdsmen, low education levels, young and middle-aged women, and nutrition status should be paid attention to in future anemia control. |
| first_indexed | 2024-04-09T22:59:32Z |
| format | Article |
| id | doaj.art-6f9e339bc7c94ba39e53ae037a1c28dc |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-09T22:59:32Z |
| publishDate | 2023-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-6f9e339bc7c94ba39e53ae037a1c28dc2023-03-22T11:03:30ZengNature PortfolioScientific Reports2045-23222023-02-011311610.1038/s41598-022-26868-7The clinical characteristics of anemia in native adults living at different altitudes of the Tibetan PlateauJie Fang0Ran Li1Dongdong Ye2Liang Chen3Luo Bu Zhuo Ma4Yinyin Zhang5Jun Zhu6Xiaodong Gao7Pengpeng Xu8Yu Zheng9Xiaoyang Li10Jianhua You11Chuanhe Jiang12Kai Qing13Fei Yue14Junmin Li15Pu Bu Wang Dui16Kai Xue17Department of Hematology, Shigatse People’s HospitalShanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital, Shanghai Jiao Tong University School of MedicineDepartment of Medical Oncology, Ruijin Hospital Wuxi Branch, Shanghai Jiao Tong University School of MedicineDepartment of Hematology, Shigatse People’s HospitalDepartment of Hematology, Shigatse People’s HospitalDepartment of Hematology, Shigatse People’s HospitalDepartment of Hematology, Shigatse People’s HospitalShanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital, Shanghai Jiao Tong University School of MedicineShanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital, Shanghai Jiao Tong University School of MedicineShanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital, Shanghai Jiao Tong University School of MedicineShanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital, Shanghai Jiao Tong University School of MedicineShanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital, Shanghai Jiao Tong University School of MedicineShanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital, Shanghai Jiao Tong University School of MedicineShanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital, Shanghai Jiao Tong University School of MedicineDepartment of Hematology, Shigatse People’s HospitalShanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital, Shanghai Jiao Tong University School of MedicineDepartment of Hematology, Shigatse People’s HospitalDepartment of Hematology, Shigatse People’s HospitalAbstract To provide evidence-based medicine references for formulating prevention and control policies in plateau areas, we explore the characteristics of anemia patients in Tibet (the plateau areas of China), especially those located at an altitude above 4500 m. We collected clinical data from 379 Tibetan anemia patients over the age of 18 years. We found those female patients accounted for the majority of Tibetan anemia patients. Almost half of the anemia patients aged from 28 to 47 years. The percentage of severe anemia and extremely severe anemia was 45.4% and 2.4%, respectively. 88.7% of patients are engaged in agriculture and animal husbandry, and 81.5% of patients just graduated from primary school or below. The most common causes of anemia were nutritional anemia, especially iron-deficiency anemia. At high-altitude localities, folic acid-deficiency anemia needs more attention. Overall, this study showed that altitude influences the incidence, severity, and cause of anemia. Peasants and herdsmen, low education levels, young and middle-aged women, and nutrition status should be paid attention to in future anemia control.https://doi.org/10.1038/s41598-022-26868-7 |
| spellingShingle | Jie Fang Ran Li Dongdong Ye Liang Chen Luo Bu Zhuo Ma Yinyin Zhang Jun Zhu Xiaodong Gao Pengpeng Xu Yu Zheng Xiaoyang Li Jianhua You Chuanhe Jiang Kai Qing Fei Yue Junmin Li Pu Bu Wang Dui Kai Xue The clinical characteristics of anemia in native adults living at different altitudes of the Tibetan Plateau Scientific Reports |
| title | The clinical characteristics of anemia in native adults living at different altitudes of the Tibetan Plateau |
| title_full | The clinical characteristics of anemia in native adults living at different altitudes of the Tibetan Plateau |
| title_fullStr | The clinical characteristics of anemia in native adults living at different altitudes of the Tibetan Plateau |
| title_full_unstemmed | The clinical characteristics of anemia in native adults living at different altitudes of the Tibetan Plateau |
| title_short | The clinical characteristics of anemia in native adults living at different altitudes of the Tibetan Plateau |
| title_sort | clinical characteristics of anemia in native adults living at different altitudes of the tibetan plateau |
| url | https://doi.org/10.1038/s41598-022-26868-7 |
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