Optical Coherence Tomography in Inflammatory and Neoplastic Lesions Deforming the Choroidal Profile

The choroid is the main part of the uvea, the vascular layer of the eye that lies between the retina and the sclera. The high vascular component of the choroid makes this structure susceptible to inflammation in multisystemic diseases, as well as the most common site of metastasis in the eye. Theref...

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Main Authors: Elena Bolletta, Luca De Simone, Marco Pellegrini, Chiara Preziosa, Valentina Mastrofilippo, Chantal Adani, Pietro Gentile, Fabrizio Gozzi, Luca Cimino
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/13/12/1991
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author Elena Bolletta
Luca De Simone
Marco Pellegrini
Chiara Preziosa
Valentina Mastrofilippo
Chantal Adani
Pietro Gentile
Fabrizio Gozzi
Luca Cimino
author_facet Elena Bolletta
Luca De Simone
Marco Pellegrini
Chiara Preziosa
Valentina Mastrofilippo
Chantal Adani
Pietro Gentile
Fabrizio Gozzi
Luca Cimino
author_sort Elena Bolletta
collection DOAJ
description The choroid is the main part of the uvea, the vascular layer of the eye that lies between the retina and the sclera. The high vascular component of the choroid makes this structure susceptible to inflammation in multisystemic diseases, as well as the most common site of metastasis in the eye. Therefore, the choroid is involved in many pathological conditions, from uveitis to intraocular tumors. Differentiating between inflammatory and neoplastic lesions deforming the choroidal profile can sometimes be challenging. In addition, scleral disorders can also deform the choroidal profile. Choroidal imaging includes ophthalmic ultrasonography, indocyanine green angiography, and optical coherence tomography (OCT). Recent advances in choroidal imaging techniques, such as enhanced depth imaging optical coherence tomography (EDI-OCT) and swept-source optical coherence tomography (SS-OCT), have facilitated an in-depth analysis of the choroid. The purpose of this review article is to report on and highlight the most common OCT findings to help in the differential diagnosis between inflammatory and neoplastic lesions deforming the choroidal profile.
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spelling doaj.art-6f9f347b2588419597e61923d8a882672023-11-18T09:59:35ZengMDPI AGDiagnostics2075-44182023-06-011312199110.3390/diagnostics13121991Optical Coherence Tomography in Inflammatory and Neoplastic Lesions Deforming the Choroidal ProfileElena Bolletta0Luca De Simone1Marco Pellegrini2Chiara Preziosa3Valentina Mastrofilippo4Chantal Adani5Pietro Gentile6Fabrizio Gozzi7Luca Cimino8Ocular Immunology Unit, Azienda USL-IRCCS, 42123 Reggio Emilia, ItalyOcular Immunology Unit, Azienda USL-IRCCS, 42123 Reggio Emilia, ItalyDepartment of Biomedical and Clinical Science “Luigi Sacco”, Luigi Sacco Hospital, University of Milan, 20157 Milan, ItalyDepartment of Biomedical and Clinical Science “Luigi Sacco”, Luigi Sacco Hospital, University of Milan, 20157 Milan, ItalyOcular Immunology Unit, Azienda USL-IRCCS, 42123 Reggio Emilia, ItalyOcular Immunology Unit, Azienda USL-IRCCS, 42123 Reggio Emilia, ItalyOcular Immunology Unit, Azienda USL-IRCCS, 42123 Reggio Emilia, ItalyOcular Immunology Unit, Azienda USL-IRCCS, 42123 Reggio Emilia, ItalyOcular Immunology Unit, Azienda USL-IRCCS, 42123 Reggio Emilia, ItalyThe choroid is the main part of the uvea, the vascular layer of the eye that lies between the retina and the sclera. The high vascular component of the choroid makes this structure susceptible to inflammation in multisystemic diseases, as well as the most common site of metastasis in the eye. Therefore, the choroid is involved in many pathological conditions, from uveitis to intraocular tumors. Differentiating between inflammatory and neoplastic lesions deforming the choroidal profile can sometimes be challenging. In addition, scleral disorders can also deform the choroidal profile. Choroidal imaging includes ophthalmic ultrasonography, indocyanine green angiography, and optical coherence tomography (OCT). Recent advances in choroidal imaging techniques, such as enhanced depth imaging optical coherence tomography (EDI-OCT) and swept-source optical coherence tomography (SS-OCT), have facilitated an in-depth analysis of the choroid. The purpose of this review article is to report on and highlight the most common OCT findings to help in the differential diagnosis between inflammatory and neoplastic lesions deforming the choroidal profile.https://www.mdpi.com/2075-4418/13/12/1991choroidchoroidal granulomauveitistumoroptical coherence tomographyenhanced depth imaging
spellingShingle Elena Bolletta
Luca De Simone
Marco Pellegrini
Chiara Preziosa
Valentina Mastrofilippo
Chantal Adani
Pietro Gentile
Fabrizio Gozzi
Luca Cimino
Optical Coherence Tomography in Inflammatory and Neoplastic Lesions Deforming the Choroidal Profile
Diagnostics
choroid
choroidal granuloma
uveitis
tumor
optical coherence tomography
enhanced depth imaging
title Optical Coherence Tomography in Inflammatory and Neoplastic Lesions Deforming the Choroidal Profile
title_full Optical Coherence Tomography in Inflammatory and Neoplastic Lesions Deforming the Choroidal Profile
title_fullStr Optical Coherence Tomography in Inflammatory and Neoplastic Lesions Deforming the Choroidal Profile
title_full_unstemmed Optical Coherence Tomography in Inflammatory and Neoplastic Lesions Deforming the Choroidal Profile
title_short Optical Coherence Tomography in Inflammatory and Neoplastic Lesions Deforming the Choroidal Profile
title_sort optical coherence tomography in inflammatory and neoplastic lesions deforming the choroidal profile
topic choroid
choroidal granuloma
uveitis
tumor
optical coherence tomography
enhanced depth imaging
url https://www.mdpi.com/2075-4418/13/12/1991
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