Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain

Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain

<p>Abstract</p> <p>Background</p> <p>Variations in sortilin-related receptor (SORL1) expression and function have been implicated in Alzheimers Disease (AD). Here, to gain insights into SORL1, we evaluated SORL1 expression and splicing as a function of AD and AD neuropa...

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Main Authors: Liu Qiang, Markesbery William R, Schmitt Frederick A, Peterson Shawn L, Simmons Christopher R, Furman Jennifer L, Simpson James F, Ling I-Fang, Grear Karrie E, Crook Julia E, Younkin Steven G, Bu Guojun, Estus Steven
Format: Article
Language:English
Published: BMC 2009-11-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/4/1/46

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