Enhancer RNAs stimulate Pol II pause release by harnessing multivalent interactions to NELF
Enhancer RNAs (eRNAs) can stimulate gene transcription through various mechanisms. Here, the authors identify the molecular features within eRNAs that are critical for their action in facilitating RNA Polymerase II release from the paused state.
Bibliographic Details
| Main Authors: |
Vladyslava Gorbovytska,
Seung-Kyoon Kim,
Filiz Kuybu,
Michael Götze,
Dahun Um,
Keunsoo Kang,
Andreas Pittroff,
Theresia Brennecke,
Lisa-Marie Schneider,
Alexander Leitner,
Tae-Kyung Kim,
Claus-D. Kuhn |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2022-05-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-022-29934-w
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