Intracellular Environment and agr System Affect Colony Size Heterogeneity of Staphylococcus aureus

Intracellular Environment and agr System Affect Colony Size Heterogeneity of Staphylococcus aureus

Staphylococcus aureus causes chronic and relapsing infections, which may be difficult to treat. So-called small colony variants (SCVs) have been associated with chronic infections and their occurrence has been shown to increase under antibiotic pressure, low pH and intracellular localization. In cli...

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Bibliographic Details
Main Authors: Nicola Häffner, Julian Bär, Vanina Dengler Haunreiter, Srikanth Mairpady Shambat, Kati Seidl, Heidi A. Crosby, Alexander R. Horswill, Annelies S. Zinkernagel
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Microbiology
Subjects:
Staphylococcus aureus
small colony variants
intracellular survival
agr system
intracellular pH
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01415/full

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