Comprehensive Assessment of Copy Number Alterations Uncovers Recurrent <i>AIFM3</i> and <i>DLK1</i> Copy Gain in Medullary Thyroid Carcinoma

Comprehensive Assessment of Copy Number Alterations Uncovers Recurrent <i>AIFM3</i> and <i>DLK1</i> Copy Gain in Medullary Thyroid Carcinoma

Medullary thyroid carcinoma (MTC) is a malignant tumor originating from thyroid C-cells that can occur either in sporadic (70–80%) or hereditary (20–30%) form. In this study we aimed to identify recurrent copy number alterations (CNA) that might be related to the pathogenesis or progression of MTC....

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Bibliographic Details
Main Authors: Aline Neves Araujo, Cléber Pinto Camacho, Thais Biude Mendes, Susan Chow Lindsey, Lais Moraes, Marta Miyazawa, Rosana Delcelo, Renata Pellegrino, Diego Robles Mazzotti, Rui Monteiro de Barros Maciel, Janete Maria Cerutti
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
medullary thyroid carcinoma
RET
copy number alteration
AIFM3
DLK1
Online Access:https://www.mdpi.com/2072-6694/13/2/218

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