Cytotoxic, genotoxic, and oxidative stress-related effects of lysergic acid diethylamide (LSD) and phencyclidine (PCP) in the human neuroblastoma SH-SY5Y cell line

Cytotoxic, genotoxic, and oxidative stress-related effects of lysergic acid diethylamide (LSD) and phencyclidine (PCP) in the human neuroblastoma SH-SY5Y cell line

Lysergic acid diethylamide (LSD) is a classic hallucinogen, widely abused for decades, while phencyclidine (PCP) has increased in popularity in recent years, especially among the adolescents. Very little is known about the general toxicity of these compounds, especially about their possible neurotox...

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Bibliographic Details
Main Authors: Jurič Andreja, Zandona Antonio, Lovaković Blanka Tariba, Rašić Dubravka, Pizent Alica, Kozina Goran, Katalinić Maja, Vrdoljak Ana Lucić, Karačonji Irena Brčić
Format: Article
Language:English
Published: Sciendo 2021-12-01
Series:Arhiv za Higijenu Rada i Toksikologiju
Subjects:
antioxidant enzymes
cell viability
dna damage
gsh
hallucinogenic drugs
psychoactive substances
ros
toxicity
antioksidacijski enzimi
halucinogene droge
lsd
oštećenje dna
pcp
psihoaktivne tvari
toksičnost
vijabilnost stanica
Online Access:https://doi.org/10.2478/aiht-2021-72-3604

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