First method for dissolving zinc thiazole and re-evaluation of its antibacterial properties against rice bacterial blight disease
Abstract Rice bacterial blight (BB), caused by Xanthomonas oryzae pv. oryzae (Xoo), is one of the most destructive diseases in rice-growing regions worldwide. Zinc thiazole is a novel bactericide and has been applied for BB control for 10 years. However, zinc thiazole is highly insoluble in water an...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2019-10-01
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| Series: | Phytopathology Research |
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| Online Access: | http://link.springer.com/article/10.1186/s42483-019-0036-4 |
| _version_ | 1819171748949524480 |
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| author | Xian Chen Lan Zhou Pedro Laborda Yancun Zhao Kaihuai Li Fengquan Liu |
| author_facet | Xian Chen Lan Zhou Pedro Laborda Yancun Zhao Kaihuai Li Fengquan Liu |
| author_sort | Xian Chen |
| collection | DOAJ |
| description | Abstract Rice bacterial blight (BB), caused by Xanthomonas oryzae pv. oryzae (Xoo), is one of the most destructive diseases in rice-growing regions worldwide. Zinc thiazole is a novel bactericide and has been applied for BB control for 10 years. However, zinc thiazole is highly insoluble in water and in most organic solvents. In this work, we found for the first time that zinc thiazole can be dissolved in dimethyl sulfoxide (DMSO), and the solubility of zinc thiazole in DMSO is more than 20 mg/mL. Dissolved zinc thiazole at 25 μg/mL significantly inhibited the growth of Xoo by 58.81%. Interestingly, zinc thiazole at 25 μg/mL enhanced the cell division and altered the cell wall integrity of Xoo. The application of dissolved zinc thiazole at 100 μg/mL reduced the incidence of rice bacterial blight (BB) by providing 64.71% control efficacy, while zinc thiazole as suspension concentrate (SC) at 100 μg/mL only provided 43.42% control efficacy. Taken together, this study provides for the first time a method for dissolving zinc thiazole, and may help to better understand the antibacterial mechanism of zinc thiazole. |
| first_indexed | 2024-12-22T19:56:14Z |
| format | Article |
| id | doaj.art-6fa9a7ff844a47fab967482089d35dcf |
| institution | Directory Open Access Journal |
| issn | 2524-4167 |
| language | English |
| last_indexed | 2024-12-22T19:56:14Z |
| publishDate | 2019-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Phytopathology Research |
| spelling | doaj.art-6fa9a7ff844a47fab967482089d35dcf2022-12-21T18:14:24ZengBMCPhytopathology Research2524-41672019-10-011111010.1186/s42483-019-0036-4First method for dissolving zinc thiazole and re-evaluation of its antibacterial properties against rice bacterial blight diseaseXian Chen0Lan Zhou1Pedro Laborda2Yancun Zhao3Kaihuai Li4Fengquan Liu5Institute of Plant Protection, Jiangsu Key Laboratory for Food Quality and Safety–State Key Laboratory Cultivation Base of Ministry of Science and Technology, Jiangsu Academy of Agricultural SciencesAcademy of Agricultural Science of YanbianSchool of Life Sciences, Nantong UniversityInstitute of Plant Protection, Jiangsu Key Laboratory for Food Quality and Safety–State Key Laboratory Cultivation Base of Ministry of Science and Technology, Jiangsu Academy of Agricultural SciencesInstitute of Plant Protection, Jiangsu Key Laboratory for Food Quality and Safety–State Key Laboratory Cultivation Base of Ministry of Science and Technology, Jiangsu Academy of Agricultural SciencesInstitute of Plant Protection, Jiangsu Key Laboratory for Food Quality and Safety–State Key Laboratory Cultivation Base of Ministry of Science and Technology, Jiangsu Academy of Agricultural SciencesAbstract Rice bacterial blight (BB), caused by Xanthomonas oryzae pv. oryzae (Xoo), is one of the most destructive diseases in rice-growing regions worldwide. Zinc thiazole is a novel bactericide and has been applied for BB control for 10 years. However, zinc thiazole is highly insoluble in water and in most organic solvents. In this work, we found for the first time that zinc thiazole can be dissolved in dimethyl sulfoxide (DMSO), and the solubility of zinc thiazole in DMSO is more than 20 mg/mL. Dissolved zinc thiazole at 25 μg/mL significantly inhibited the growth of Xoo by 58.81%. Interestingly, zinc thiazole at 25 μg/mL enhanced the cell division and altered the cell wall integrity of Xoo. The application of dissolved zinc thiazole at 100 μg/mL reduced the incidence of rice bacterial blight (BB) by providing 64.71% control efficacy, while zinc thiazole as suspension concentrate (SC) at 100 μg/mL only provided 43.42% control efficacy. Taken together, this study provides for the first time a method for dissolving zinc thiazole, and may help to better understand the antibacterial mechanism of zinc thiazole.http://link.springer.com/article/10.1186/s42483-019-0036-4Zinc thiazoleSolubilityAntibacterial effectRice bacterial blightXanthomonas oryzae pv. oryzae |
| spellingShingle | Xian Chen Lan Zhou Pedro Laborda Yancun Zhao Kaihuai Li Fengquan Liu First method for dissolving zinc thiazole and re-evaluation of its antibacterial properties against rice bacterial blight disease Phytopathology Research Zinc thiazole Solubility Antibacterial effect Rice bacterial blight Xanthomonas oryzae pv. oryzae |
| title | First method for dissolving zinc thiazole and re-evaluation of its antibacterial properties against rice bacterial blight disease |
| title_full | First method for dissolving zinc thiazole and re-evaluation of its antibacterial properties against rice bacterial blight disease |
| title_fullStr | First method for dissolving zinc thiazole and re-evaluation of its antibacterial properties against rice bacterial blight disease |
| title_full_unstemmed | First method for dissolving zinc thiazole and re-evaluation of its antibacterial properties against rice bacterial blight disease |
| title_short | First method for dissolving zinc thiazole and re-evaluation of its antibacterial properties against rice bacterial blight disease |
| title_sort | first method for dissolving zinc thiazole and re evaluation of its antibacterial properties against rice bacterial blight disease |
| topic | Zinc thiazole Solubility Antibacterial effect Rice bacterial blight Xanthomonas oryzae pv. oryzae |
| url | http://link.springer.com/article/10.1186/s42483-019-0036-4 |
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