Analysis of recipient and graft survival after primary and second kidney transplantation
Objective: to evaluate the 1- and 5-year graft and recipient survival after primary and second kidney transplantation, to compare the outcomes depending on the age of recipients.Material and methods. The treatment outcomes for 364 patients who underwent kidney transplantation at Sklifosovsky Researc...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
2021-07-01
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| Series: | Vestnik Transplantologii i Iskusstvennyh Organov |
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| Online Access: | https://journal.transpl.ru/vtio/article/view/1210 |
| _version_ | 1797871933143908352 |
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| author | A. V. Pinchuk N. V. Shmarina I. V. Dmitriev V. E. Vinogradov A. I. Kazantsev |
| author_facet | A. V. Pinchuk N. V. Shmarina I. V. Dmitriev V. E. Vinogradov A. I. Kazantsev |
| author_sort | A. V. Pinchuk |
| collection | DOAJ |
| description | Objective: to evaluate the 1- and 5-year graft and recipient survival after primary and second kidney transplantation, to compare the outcomes depending on the age of recipients.Material and methods. The treatment outcomes for 364 patients who underwent kidney transplantation at Sklifosovsky Research Institute of Emergency Care, Moscow over the period from 2007 to 2019. Of these, 213 patients underwent kidney transplantation for the first time, while 151 patients were having a second transplantation. We analyzed the effect of previous transplants, as well as the age of the recipients on long-term survival rates.Results. No significant difference in 1- and 5-year survival of kidney recipients after primary and second transplantations was found. In contrast, the long-term graft survival significantly depended on this criterion and turned out to be significantly higher after primary transplantations. The 1- and 5-year survival of older recipients was lower than the survival of younger recipients after primary and second kidney transplantation. The 1-year graft survival after primary kidney transplantation was higher in young recipients than in older recipients of the same group, however, but there were no significant differences in the 5-year graft survival. After second transplantations, there were no significant differences in the 1- and 5-year graft survival depending on the age of recipients.Conclusion. A history of previous transplantation is an important factor in kidney transplantation outcome, which must be taken into account in clinical practice. |
| first_indexed | 2024-04-10T00:50:43Z |
| format | Article |
| id | doaj.art-6fab67fe70e3429ca6d3b64fb68a223e |
| institution | Directory Open Access Journal |
| issn | 1995-1191 |
| language | Russian |
| last_indexed | 2024-04-10T00:50:43Z |
| publishDate | 2021-07-01 |
| publisher | Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov |
| record_format | Article |
| series | Vestnik Transplantologii i Iskusstvennyh Organov |
| spelling | doaj.art-6fab67fe70e3429ca6d3b64fb68a223e2023-03-13T10:37:27ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovVestnik Transplantologii i Iskusstvennyh Organov1995-11912021-07-01232212910.15825/1995-1191-2021-2-21-29972Analysis of recipient and graft survival after primary and second kidney transplantationA. V. Pinchuk0N. V. Shmarina1I. V. Dmitriev2V. E. Vinogradov3A. I. Kazantsev4Sklifosovsky Research Institute of Emergency Care; Evdokimov Moscow State University of Medicine and Dentistry; Research Institute of Healthcare and Medical ManagementSklifosovsky Research Institute of Emergency CareSklifosovsky Research Institute of Emergency CareResearch Institute of Healthcare and Medical Management; City Clinical Hospital No.52Sklifosovsky Research Institute of Emergency CareObjective: to evaluate the 1- and 5-year graft and recipient survival after primary and second kidney transplantation, to compare the outcomes depending on the age of recipients.Material and methods. The treatment outcomes for 364 patients who underwent kidney transplantation at Sklifosovsky Research Institute of Emergency Care, Moscow over the period from 2007 to 2019. Of these, 213 patients underwent kidney transplantation for the first time, while 151 patients were having a second transplantation. We analyzed the effect of previous transplants, as well as the age of the recipients on long-term survival rates.Results. No significant difference in 1- and 5-year survival of kidney recipients after primary and second transplantations was found. In contrast, the long-term graft survival significantly depended on this criterion and turned out to be significantly higher after primary transplantations. The 1- and 5-year survival of older recipients was lower than the survival of younger recipients after primary and second kidney transplantation. The 1-year graft survival after primary kidney transplantation was higher in young recipients than in older recipients of the same group, however, but there were no significant differences in the 5-year graft survival. After second transplantations, there were no significant differences in the 1- and 5-year graft survival depending on the age of recipients.Conclusion. A history of previous transplantation is an important factor in kidney transplantation outcome, which must be taken into account in clinical practice.https://journal.transpl.ru/vtio/article/view/1210primary kidney transplantationsecond kidney transplantationoutcomesrecipient survivalkidney graft survival |
| spellingShingle | A. V. Pinchuk N. V. Shmarina I. V. Dmitriev V. E. Vinogradov A. I. Kazantsev Analysis of recipient and graft survival after primary and second kidney transplantation Vestnik Transplantologii i Iskusstvennyh Organov primary kidney transplantation second kidney transplantation outcomes recipient survival kidney graft survival |
| title | Analysis of recipient and graft survival after primary and second kidney transplantation |
| title_full | Analysis of recipient and graft survival after primary and second kidney transplantation |
| title_fullStr | Analysis of recipient and graft survival after primary and second kidney transplantation |
| title_full_unstemmed | Analysis of recipient and graft survival after primary and second kidney transplantation |
| title_short | Analysis of recipient and graft survival after primary and second kidney transplantation |
| title_sort | analysis of recipient and graft survival after primary and second kidney transplantation |
| topic | primary kidney transplantation second kidney transplantation outcomes recipient survival kidney graft survival |
| url | https://journal.transpl.ru/vtio/article/view/1210 |
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