Imaging and clinical perspectives of rhino-orbito-cerebral mucormycosis: An epidemic born out of a pandemic
Purpose: To study the imaging and clinical perspectives of a recent epidemic of rhinocerebral mucormycosis during the COVID-19 (coronavirus disease) pandemic in India. Materials and Methods: This retrospective study included clinical and imaging data of 24 diagnosed cases of acute rhinocerebral muco...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | MGM Journal of Medical Sciences |
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| Online Access: | http://www.mgmjms.com/article.asp?issn=2347-7946;year=2022;volume=9;issue=3;spage=296;epage=302;aulast=Qaseem |
| _version_ | 1811240780952502272 |
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| author | Syed M Danish Qaseem Mohd Monis Aiman Ibbrahim Mohd Khalid |
| author_facet | Syed M Danish Qaseem Mohd Monis Aiman Ibbrahim Mohd Khalid |
| author_sort | Syed M Danish Qaseem |
| collection | DOAJ |
| description | Purpose: To study the imaging and clinical perspectives of a recent epidemic of rhinocerebral mucormycosis during the COVID-19 (coronavirus disease) pandemic in India. Materials and Methods: This retrospective study included clinical and imaging data of 24 diagnosed cases of acute rhinocerebral mucormycosis who were presented to our hospital in May 2021. The clinical profile and imaging data of the patients were documented. Results: 18 patients (75.0%) had moderate to severe COVID-19 illness with a history of oral or intravenous corticosteroid intake. 19 patients (79.2%) had presented with hyperglycemia at the time of admission. Nasal discharges with or without black crusts and facial swelling (79.2%) were the most commonly reported complaints, followed by headaches or facial pain (62.5%). All cases demonstrated the involvement of one or more paranasal sinuses in imaging, with predominantly unilateral involvement. Extra sinusoidal involvement was commonly seen, with abnormalities seen in retromaxillary and masticator space, orbit, face, oral cavity, pterygopalatine fossa, and deep spaces of the neck, cavernous sinus, and brain. Conclusion: An upsurge of mucormycosis cases during the COVID-19 pandemic appears to be closely related to uncontrolled hyperglycemia and corticosteroid therapy. Computed tomography (CT) and magnetic resonance (MR) imaging are invaluable in establishing an early diagnosis, defining the extent of disease, and helping in immediate surgical planning. |
| first_indexed | 2024-04-12T13:26:24Z |
| format | Article |
| id | doaj.art-6fabb6477ce1408a9e24fad074186384 |
| institution | Directory Open Access Journal |
| issn | 2347-7946 2347-7962 |
| language | English |
| last_indexed | 2024-04-12T13:26:24Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | MGM Journal of Medical Sciences |
| spelling | doaj.art-6fabb6477ce1408a9e24fad0741863842022-12-22T03:31:19ZengWolters Kluwer Medknow PublicationsMGM Journal of Medical Sciences2347-79462347-79622022-01-019329630210.4103/mgmj.mgmj_89_22Imaging and clinical perspectives of rhino-orbito-cerebral mucormycosis: An epidemic born out of a pandemicSyed M Danish QaseemMohd MonisAiman IbbrahimMohd KhalidPurpose: To study the imaging and clinical perspectives of a recent epidemic of rhinocerebral mucormycosis during the COVID-19 (coronavirus disease) pandemic in India. Materials and Methods: This retrospective study included clinical and imaging data of 24 diagnosed cases of acute rhinocerebral mucormycosis who were presented to our hospital in May 2021. The clinical profile and imaging data of the patients were documented. Results: 18 patients (75.0%) had moderate to severe COVID-19 illness with a history of oral or intravenous corticosteroid intake. 19 patients (79.2%) had presented with hyperglycemia at the time of admission. Nasal discharges with or without black crusts and facial swelling (79.2%) were the most commonly reported complaints, followed by headaches or facial pain (62.5%). All cases demonstrated the involvement of one or more paranasal sinuses in imaging, with predominantly unilateral involvement. Extra sinusoidal involvement was commonly seen, with abnormalities seen in retromaxillary and masticator space, orbit, face, oral cavity, pterygopalatine fossa, and deep spaces of the neck, cavernous sinus, and brain. Conclusion: An upsurge of mucormycosis cases during the COVID-19 pandemic appears to be closely related to uncontrolled hyperglycemia and corticosteroid therapy. Computed tomography (CT) and magnetic resonance (MR) imaging are invaluable in establishing an early diagnosis, defining the extent of disease, and helping in immediate surgical planning.http://www.mgmjms.com/article.asp?issn=2347-7946;year=2022;volume=9;issue=3;spage=296;epage=302;aulast=Qaseemcovid-19corticosteroidhyperglycemiaimagingrhinocerebral mucormycosis |
| spellingShingle | Syed M Danish Qaseem Mohd Monis Aiman Ibbrahim Mohd Khalid Imaging and clinical perspectives of rhino-orbito-cerebral mucormycosis: An epidemic born out of a pandemic MGM Journal of Medical Sciences covid-19 corticosteroid hyperglycemia imaging rhinocerebral mucormycosis |
| title | Imaging and clinical perspectives of rhino-orbito-cerebral mucormycosis: An epidemic born out of a pandemic |
| title_full | Imaging and clinical perspectives of rhino-orbito-cerebral mucormycosis: An epidemic born out of a pandemic |
| title_fullStr | Imaging and clinical perspectives of rhino-orbito-cerebral mucormycosis: An epidemic born out of a pandemic |
| title_full_unstemmed | Imaging and clinical perspectives of rhino-orbito-cerebral mucormycosis: An epidemic born out of a pandemic |
| title_short | Imaging and clinical perspectives of rhino-orbito-cerebral mucormycosis: An epidemic born out of a pandemic |
| title_sort | imaging and clinical perspectives of rhino orbito cerebral mucormycosis an epidemic born out of a pandemic |
| topic | covid-19 corticosteroid hyperglycemia imaging rhinocerebral mucormycosis |
| url | http://www.mgmjms.com/article.asp?issn=2347-7946;year=2022;volume=9;issue=3;spage=296;epage=302;aulast=Qaseem |
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