Outflow tract septation and the aortic arch system in reptiles: lessons for understanding the mammalian heart

Outflow tract septation and the aortic arch system in reptiles: lessons for understanding the mammalian heart

Abstract Background Cardiac outflow tract patterning and cell contribution are studied using an evo-devo approach to reveal insight into the development of aorto-pulmonary septation. Results We studied embryonic stages of reptile hearts (lizard, turtle and crocodile) and compared these to avian and...

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Bibliographic Details
Main Authors: Robert E. Poelmann, Adriana C. Gittenberger-de Groot, Marcel W. M. Biermans, Anne I. Dolfing, Armand Jagessar, Sam van Hattum, Amanda Hoogenboom, Lambertus J. Wisse, Rebecca Vicente-Steijn, Merijn A. G. de Bakker, Freek J. Vonk, Tatsuya Hirasawa, Shigeru Kuratani, Michael K. Richardson
Format: Article
Language:English
Published: BMC 2017-05-01
Series:EvoDevo
Subjects:
Cardiac development
Outflow tract cushions
Aorto-pulmonary septation
Flow divider
Neural crest
Second heart field
Online Access:http://link.springer.com/article/10.1186/s13227-017-0072-z

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