Evaluation of ultrasound sensors for transcranial photoacoustic sensing and imaging
Photoacoustic imaging through skull bone causes strong attenuation and distortion of the acoustic wavefront, which diminishes image contrast and resolution. As a result, transcranial photoacoustic measurements in humans have been challenging to demonstrate. In this study, we investigated the acousti...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-10-01
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| Series: | Photoacoustics |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S221359792300109X |
| _version_ | 1797643601501487104 |
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| author | Thomas Kirchner Claus Villringer Jan Laufer |
| author_facet | Thomas Kirchner Claus Villringer Jan Laufer |
| author_sort | Thomas Kirchner |
| collection | DOAJ |
| description | Photoacoustic imaging through skull bone causes strong attenuation and distortion of the acoustic wavefront, which diminishes image contrast and resolution. As a result, transcranial photoacoustic measurements in humans have been challenging to demonstrate. In this study, we investigated the acoustic transmission through the human skull to design an ultrasound sensor suitable for transcranial PA imaging and sensing. We measured the frequency dependent losses of human cranial bones ex vivo, compared the performance of a range of piezoelectric and optical ultrasound sensors, and imaged skull phantoms using a PA tomograph based on a planar Fabry–Perot sensor. All transcranial photoacoustic measurements show the typical effects of frequency and thickness dependent attenuation and aberration associated with acoustic propagation through bone. The performance of plano-concave optical resonator ultrasound sensors was found to be highly suitable for transcranial photoacoustic measurements. |
| first_indexed | 2024-03-11T14:17:16Z |
| format | Article |
| id | doaj.art-6fb7ab55b6cd4518813312ee90baaf56 |
| institution | Directory Open Access Journal |
| issn | 2213-5979 |
| language | English |
| last_indexed | 2024-03-11T14:17:16Z |
| publishDate | 2023-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Photoacoustics |
| spelling | doaj.art-6fb7ab55b6cd4518813312ee90baaf562023-11-01T04:47:10ZengElsevierPhotoacoustics2213-59792023-10-0133100556Evaluation of ultrasound sensors for transcranial photoacoustic sensing and imagingThomas Kirchner0Claus Villringer1Jan Laufer2Institut für Physik, Martin-Luther-Universität Halle-Wittenberg, Von-Danckelmann-Platz 3, 06120 Halle (Saale), Germany; Corresponding author.Institut für Physik, Martin-Luther-Universität Halle-Wittenberg, Von-Danckelmann-Platz 3, 06120 Halle (Saale), Germany; Technische Hochschule Wildau, Hochschulring 1, 15745 Wildau, GermanyInstitut für Physik, Martin-Luther-Universität Halle-Wittenberg, Von-Danckelmann-Platz 3, 06120 Halle (Saale), GermanyPhotoacoustic imaging through skull bone causes strong attenuation and distortion of the acoustic wavefront, which diminishes image contrast and resolution. As a result, transcranial photoacoustic measurements in humans have been challenging to demonstrate. In this study, we investigated the acoustic transmission through the human skull to design an ultrasound sensor suitable for transcranial PA imaging and sensing. We measured the frequency dependent losses of human cranial bones ex vivo, compared the performance of a range of piezoelectric and optical ultrasound sensors, and imaged skull phantoms using a PA tomograph based on a planar Fabry–Perot sensor. All transcranial photoacoustic measurements show the typical effects of frequency and thickness dependent attenuation and aberration associated with acoustic propagation through bone. The performance of plano-concave optical resonator ultrasound sensors was found to be highly suitable for transcranial photoacoustic measurements.http://www.sciencedirect.com/science/article/pii/S221359792300109XTranscranialUltrasound sensorsPhotoacousticOptoacoustic |
| spellingShingle | Thomas Kirchner Claus Villringer Jan Laufer Evaluation of ultrasound sensors for transcranial photoacoustic sensing and imaging Photoacoustics Transcranial Ultrasound sensors Photoacoustic Optoacoustic |
| title | Evaluation of ultrasound sensors for transcranial photoacoustic sensing and imaging |
| title_full | Evaluation of ultrasound sensors for transcranial photoacoustic sensing and imaging |
| title_fullStr | Evaluation of ultrasound sensors for transcranial photoacoustic sensing and imaging |
| title_full_unstemmed | Evaluation of ultrasound sensors for transcranial photoacoustic sensing and imaging |
| title_short | Evaluation of ultrasound sensors for transcranial photoacoustic sensing and imaging |
| title_sort | evaluation of ultrasound sensors for transcranial photoacoustic sensing and imaging |
| topic | Transcranial Ultrasound sensors Photoacoustic Optoacoustic |
| url | http://www.sciencedirect.com/science/article/pii/S221359792300109X |
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