Medical nutrition therapy in hospitalized patients with pemphigus vulgaris

Dysphagia due to involvement of the oral, pharyngolaryngeal, and esophageal mucosa and increased catabolism due to epidermal shedding can contribute to a decline in nutritional status in pemphigus vulgaris (PV) patients. On the other hand, decreased lean body mass is associated with immune system im...

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Main Authors: Bintari Anindhita, Nurul Ratna Mutu Manikam
Format: Article
Language:English
Published: Indonesian Nutrition Association 2023-08-01
Series:World Nutrition Journal
Subjects:
Online Access:https://worldnutrijournal.org/OJS/index.php/WNJ/article/view/490
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author Bintari Anindhita
Nurul Ratna Mutu Manikam
author_facet Bintari Anindhita
Nurul Ratna Mutu Manikam
author_sort Bintari Anindhita
collection DOAJ
description Dysphagia due to involvement of the oral, pharyngolaryngeal, and esophageal mucosa and increased catabolism due to epidermal shedding can contribute to a decline in nutritional status in pemphigus vulgaris (PV) patients. On the other hand, decreased lean body mass is associated with immune system impairment, increased risk of infection, and delayed wound healing in PV patients, therefore, nutritional screening and assessment are necessary. Medical nutritional therapy in PV patients aims to overcome the metabolic response to the insults, prevent further malnutrition, modulate the immune system, and accelerate wound healing process. An aggressive nutritional support to minimize protein loss during the phase of mucocutaneous lesion healing is needed in patients with PV. Aside from macronutrient adequacy, micronutrients including vitamin A supplementation can be considered to accelerate wound healing process. Medical nutritional therapy including provision of adequate macronutrients, micronutrients, addressing dehydration and electrolyte imbalances should be the cornerstone of multidisciplinary treatment in PV patients.
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spelling doaj.art-6fb7c1cd1b664679a957b1cab92784ba2023-08-31T10:25:37ZengIndonesian Nutrition AssociationWorld Nutrition Journal2580-70132023-08-01701142210.25220/10.25220/WNJ.V07.i1.0004490Medical nutrition therapy in hospitalized patients with pemphigus vulgarisBintari Anindhita0Nurul Ratna Mutu Manikam1Faculty of Medicine Universitas Indonesia – dr. Cipto Mangunkusumo General Hospital. Jakarta, IndonesiaFaculty of Medicine Universitas Indonesia – dr. Cipto Mangunkusumo General Hospital. Jakarta, IndonesiaDysphagia due to involvement of the oral, pharyngolaryngeal, and esophageal mucosa and increased catabolism due to epidermal shedding can contribute to a decline in nutritional status in pemphigus vulgaris (PV) patients. On the other hand, decreased lean body mass is associated with immune system impairment, increased risk of infection, and delayed wound healing in PV patients, therefore, nutritional screening and assessment are necessary. Medical nutritional therapy in PV patients aims to overcome the metabolic response to the insults, prevent further malnutrition, modulate the immune system, and accelerate wound healing process. An aggressive nutritional support to minimize protein loss during the phase of mucocutaneous lesion healing is needed in patients with PV. Aside from macronutrient adequacy, micronutrients including vitamin A supplementation can be considered to accelerate wound healing process. Medical nutritional therapy including provision of adequate macronutrients, micronutrients, addressing dehydration and electrolyte imbalances should be the cornerstone of multidisciplinary treatment in PV patients.https://worldnutrijournal.org/OJS/index.php/WNJ/article/view/490malnutritionmedical nutrition therapypemphigus vulgariswound healingmicronutrients
spellingShingle Bintari Anindhita
Nurul Ratna Mutu Manikam
Medical nutrition therapy in hospitalized patients with pemphigus vulgaris
World Nutrition Journal
malnutrition
medical nutrition therapy
pemphigus vulgaris
wound healing
micronutrients
title Medical nutrition therapy in hospitalized patients with pemphigus vulgaris
title_full Medical nutrition therapy in hospitalized patients with pemphigus vulgaris
title_fullStr Medical nutrition therapy in hospitalized patients with pemphigus vulgaris
title_full_unstemmed Medical nutrition therapy in hospitalized patients with pemphigus vulgaris
title_short Medical nutrition therapy in hospitalized patients with pemphigus vulgaris
title_sort medical nutrition therapy in hospitalized patients with pemphigus vulgaris
topic malnutrition
medical nutrition therapy
pemphigus vulgaris
wound healing
micronutrients
url https://worldnutrijournal.org/OJS/index.php/WNJ/article/view/490
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