Associations of Dynapenic Obesity and Sarcopenic Obesity with the Risk of Complications in COVID-19
Ageing is associated with changes in body composition, such as low muscle mass (sarcopenia), decreased grip strength or physical function (dynapenia), and accumulation of fat mass. When the accumulation of fat mass synergistically accompanies low muscle mass or reduced grip strength, it results in s...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-07-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/23/15/8277 |
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| author | Laura Pérez-Campos Mayoral Carlos Alberto Matias-Cervantes Eduardo Pérez-Campos Carlos Romero Díaz Luis Ángel Laguna Barrios María del Socorro Pina Canseco Margarito Martínez Cruz Eduardo Pérez-Campos Mayoral Carlos Josué Solórzano Mata Francisco Javier Rodal Canales Héctor Martínez Ruíz María Teresa Hernández-Huerta |
| author_facet | Laura Pérez-Campos Mayoral Carlos Alberto Matias-Cervantes Eduardo Pérez-Campos Carlos Romero Díaz Luis Ángel Laguna Barrios María del Socorro Pina Canseco Margarito Martínez Cruz Eduardo Pérez-Campos Mayoral Carlos Josué Solórzano Mata Francisco Javier Rodal Canales Héctor Martínez Ruíz María Teresa Hernández-Huerta |
| author_sort | Laura Pérez-Campos Mayoral |
| collection | DOAJ |
| description | Ageing is associated with changes in body composition, such as low muscle mass (sarcopenia), decreased grip strength or physical function (dynapenia), and accumulation of fat mass. When the accumulation of fat mass synergistically accompanies low muscle mass or reduced grip strength, it results in sarcopenic obesity and dynapenic obesity, respectively. These types of obesity contribute to the increased risk of cardiovascular disease and mortality in the elderly, which could increase the damage caused by COVID-19. In this review, we associated factors that could generate a higher risk of COVID-19 complications in dynapenic obesity and sarcopenic obesity. For example, skeletal muscle regulates the expression of inflammatory cytokines and supports metabolic stress in pulmonary disease; hence, the presence of dynapenic obesity or sarcopenic obesity could be related to a poor prognosis in COVID-19 patients. |
| first_indexed | 2024-03-09T05:22:11Z |
| format | Article |
| id | doaj.art-6fbbee8fbe484ff0aff1e269509f8632 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-09T05:22:11Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-6fbbee8fbe484ff0aff1e269509f86322023-12-03T12:39:39ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672022-07-012315827710.3390/ijms23158277Associations of Dynapenic Obesity and Sarcopenic Obesity with the Risk of Complications in COVID-19Laura Pérez-Campos Mayoral0Carlos Alberto Matias-Cervantes1Eduardo Pérez-Campos2Carlos Romero Díaz3Luis Ángel Laguna Barrios4María del Socorro Pina Canseco5Margarito Martínez Cruz6Eduardo Pérez-Campos Mayoral7Carlos Josué Solórzano Mata8Francisco Javier Rodal Canales9Héctor Martínez Ruíz10María Teresa Hernández-Huerta11Centro de Investigación Facultad de Medicina UNAM-UABJO, Facultad de Medicina y Cirugía, Universidad Autónoma “Benito Juárez” de Oaxaca, Oaxaca City 68020, MexicoCONACyT, Facultad de Medicina y Cirugía, Universidad Autónoma “Benito Juárez” de Oaxaca, Oaxaca City 68020, MexicoTecnológico Nacional de México/IT Oaxaca, Oaxaca City 68030, MexicoCONACyT, Facultad de Medicina y Cirugía, Universidad Autónoma “Benito Juárez” de Oaxaca, Oaxaca City 68020, MexicoCentro de Investigación Facultad de Medicina UNAM-UABJO, Facultad de Medicina y Cirugía, Universidad Autónoma “Benito Juárez” de Oaxaca, Oaxaca City 68020, MexicoCentro de Investigación Facultad de Medicina UNAM-UABJO, Facultad de Medicina y Cirugía, Universidad Autónoma “Benito Juárez” de Oaxaca, Oaxaca City 68020, MexicoTecnológico Nacional de México/IT Oaxaca, Oaxaca City 68030, MexicoCentro de Investigación Facultad de Medicina UNAM-UABJO, Facultad de Medicina y Cirugía, Universidad Autónoma “Benito Juárez” de Oaxaca, Oaxaca City 68020, MexicoCentro de Investigación Facultad de Medicina UNAM-UABJO, Facultad de Medicina y Cirugía, Universidad Autónoma “Benito Juárez” de Oaxaca, Oaxaca City 68020, MexicoCentro de Investigación Facultad de Medicina UNAM-UABJO, Facultad de Medicina y Cirugía, Universidad Autónoma “Benito Juárez” de Oaxaca, Oaxaca City 68020, MexicoCentro de Investigación Facultad de Medicina UNAM-UABJO, Facultad de Medicina y Cirugía, Universidad Autónoma “Benito Juárez” de Oaxaca, Oaxaca City 68020, MexicoCONACyT, Facultad de Medicina y Cirugía, Universidad Autónoma “Benito Juárez” de Oaxaca, Oaxaca City 68020, MexicoAgeing is associated with changes in body composition, such as low muscle mass (sarcopenia), decreased grip strength or physical function (dynapenia), and accumulation of fat mass. When the accumulation of fat mass synergistically accompanies low muscle mass or reduced grip strength, it results in sarcopenic obesity and dynapenic obesity, respectively. These types of obesity contribute to the increased risk of cardiovascular disease and mortality in the elderly, which could increase the damage caused by COVID-19. In this review, we associated factors that could generate a higher risk of COVID-19 complications in dynapenic obesity and sarcopenic obesity. For example, skeletal muscle regulates the expression of inflammatory cytokines and supports metabolic stress in pulmonary disease; hence, the presence of dynapenic obesity or sarcopenic obesity could be related to a poor prognosis in COVID-19 patients.https://www.mdpi.com/1422-0067/23/15/8277sarcopenic obesityageingCOVID-19complicationsdynapenic obesity |
| spellingShingle | Laura Pérez-Campos Mayoral Carlos Alberto Matias-Cervantes Eduardo Pérez-Campos Carlos Romero Díaz Luis Ángel Laguna Barrios María del Socorro Pina Canseco Margarito Martínez Cruz Eduardo Pérez-Campos Mayoral Carlos Josué Solórzano Mata Francisco Javier Rodal Canales Héctor Martínez Ruíz María Teresa Hernández-Huerta Associations of Dynapenic Obesity and Sarcopenic Obesity with the Risk of Complications in COVID-19 International Journal of Molecular Sciences sarcopenic obesity ageing COVID-19 complications dynapenic obesity |
| title | Associations of Dynapenic Obesity and Sarcopenic Obesity with the Risk of Complications in COVID-19 |
| title_full | Associations of Dynapenic Obesity and Sarcopenic Obesity with the Risk of Complications in COVID-19 |
| title_fullStr | Associations of Dynapenic Obesity and Sarcopenic Obesity with the Risk of Complications in COVID-19 |
| title_full_unstemmed | Associations of Dynapenic Obesity and Sarcopenic Obesity with the Risk of Complications in COVID-19 |
| title_short | Associations of Dynapenic Obesity and Sarcopenic Obesity with the Risk of Complications in COVID-19 |
| title_sort | associations of dynapenic obesity and sarcopenic obesity with the risk of complications in covid 19 |
| topic | sarcopenic obesity ageing COVID-19 complications dynapenic obesity |
| url | https://www.mdpi.com/1422-0067/23/15/8277 |
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