A bibliometric analysis of the studies in high-altitude induced sleep disturbances and cognitive impairment research
Background: The two main symptoms at high altitude, sleep abnormalities and cognitive impairments, interact with each other. These two dysfunctions are also closely related to systemic multisystem diseases, including cerebrovascular diseases, psychiatric disorders, and immune regulatory diseases.Pur...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Physiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2023.1133059/full |
| _version_ | 1811165337666715648 |
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| author | Jiexin Zhang Songyuan Tang Chao Chen Hezhong Jiang Hai Liao Huawei Liu Li Wang Xin Chen |
| author_facet | Jiexin Zhang Songyuan Tang Chao Chen Hezhong Jiang Hai Liao Huawei Liu Li Wang Xin Chen |
| author_sort | Jiexin Zhang |
| collection | DOAJ |
| description | Background: The two main symptoms at high altitude, sleep abnormalities and cognitive impairments, interact with each other. These two dysfunctions are also closely related to systemic multisystem diseases, including cerebrovascular diseases, psychiatric disorders, and immune regulatory diseases.Purpose: To systematically analyze and visualize research on sleep disturbances and cognitive impairment at high altitudes using a bibliometrics method, and to determine future research directions by analyzing research trends and the latest hotspots.Methods: Publications from 1990 to 2022 on sleep disturbances and cognitive impairment at high altitudes were retrieved from the Web of Science. Using the R Bibliometrix software and Microsoft Excel, all data were examined statistically and qualitatively. For network visualization, the data were later exported into VOSviewer 1.6.17 and CiteSpace 6.1.R6.Results: A total of 487 articles in this area were published from 1990 to 2022. In this period, there was an overall increase in the number of publications. The United States has shown considerable importance in this sector. Bloch Konrad E was the most prolific and valuable author. The most prolific journal was High Altitude Medicine & Biology, and it has been the first choice for publishing in this field in recent years. Analysis of keyword co-occurrences suggested that research interest in the clinical manifestations of sleep disturbances and cognitive impairment caused by altitude hypoxia was mainly focused on “acute mountain-sickness,” “insomnia,” “apnea syndrome,” “depression,” “anxiety,” “Cheyne-strokes respiration,” and “pulmonary hypertension.” The mechanisms of disease development related to “oxidative stress,” “inflammation,” “hippocampus,” “prefrontal cortex,” “neurodegeneration,” and “spatial memory” in the brain have been the focus of recent research. According to burst detection analysis, “mood” and “memory impairment,” as terms with high strength, are expected to remain hot topics in the coming years. High-altitude-induced pulmonary hypertension is also in the emerging stage of research, and the treatments will continue to receive attention in the future.Conclusion: More attention is being focused on sleep disturbances and cognitive impairment at high altitudes. This work will serve as a useful reference for the clinical development of treatments for sleep disturbances and cognitive impairment induced by hypobaric hypoxia at high altitudes. |
| first_indexed | 2024-04-10T15:35:37Z |
| format | Article |
| id | doaj.art-6fbd8578b991462389550c13a0d908db |
| institution | Directory Open Access Journal |
| issn | 1664-042X |
| language | English |
| last_indexed | 2024-04-10T15:35:37Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Physiology |
| spelling | doaj.art-6fbd8578b991462389550c13a0d908db2023-02-13T06:47:57ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2023-01-011410.3389/fphys.2023.11330591133059A bibliometric analysis of the studies in high-altitude induced sleep disturbances and cognitive impairment researchJiexin Zhang0Songyuan Tang1Chao Chen2Hezhong Jiang3Hai Liao4Huawei Liu5Li Wang6Xin Chen7Department of Laboratory Medicine, The Third People’s Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University, Chengdu, Sichuan, ChinaFaculty of Life Sciences and Engineering, Southwest Jiaotong University, Chengdu, Sichuan, ChinaDepartment of Osteology, The 5th People’s Hospital of Jinan, Jinan, Shandong, ChinaFaculty of Life Sciences and Engineering, Southwest Jiaotong University, Chengdu, Sichuan, ChinaDepartment of Laboratory Medicine, The Third People’s Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University, Chengdu, Sichuan, ChinaDepartment of Laboratory Medicine, The Third People’s Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University, Chengdu, Sichuan, ChinaSichuan Baicheng Chinese Medicine Technology Co., Chengdu, Sichuan, ChinaDepartment of Laboratory Medicine, The Third People’s Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University, Chengdu, Sichuan, ChinaBackground: The two main symptoms at high altitude, sleep abnormalities and cognitive impairments, interact with each other. These two dysfunctions are also closely related to systemic multisystem diseases, including cerebrovascular diseases, psychiatric disorders, and immune regulatory diseases.Purpose: To systematically analyze and visualize research on sleep disturbances and cognitive impairment at high altitudes using a bibliometrics method, and to determine future research directions by analyzing research trends and the latest hotspots.Methods: Publications from 1990 to 2022 on sleep disturbances and cognitive impairment at high altitudes were retrieved from the Web of Science. Using the R Bibliometrix software and Microsoft Excel, all data were examined statistically and qualitatively. For network visualization, the data were later exported into VOSviewer 1.6.17 and CiteSpace 6.1.R6.Results: A total of 487 articles in this area were published from 1990 to 2022. In this period, there was an overall increase in the number of publications. The United States has shown considerable importance in this sector. Bloch Konrad E was the most prolific and valuable author. The most prolific journal was High Altitude Medicine & Biology, and it has been the first choice for publishing in this field in recent years. Analysis of keyword co-occurrences suggested that research interest in the clinical manifestations of sleep disturbances and cognitive impairment caused by altitude hypoxia was mainly focused on “acute mountain-sickness,” “insomnia,” “apnea syndrome,” “depression,” “anxiety,” “Cheyne-strokes respiration,” and “pulmonary hypertension.” The mechanisms of disease development related to “oxidative stress,” “inflammation,” “hippocampus,” “prefrontal cortex,” “neurodegeneration,” and “spatial memory” in the brain have been the focus of recent research. According to burst detection analysis, “mood” and “memory impairment,” as terms with high strength, are expected to remain hot topics in the coming years. High-altitude-induced pulmonary hypertension is also in the emerging stage of research, and the treatments will continue to receive attention in the future.Conclusion: More attention is being focused on sleep disturbances and cognitive impairment at high altitudes. This work will serve as a useful reference for the clinical development of treatments for sleep disturbances and cognitive impairment induced by hypobaric hypoxia at high altitudes.https://www.frontiersin.org/articles/10.3389/fphys.2023.1133059/fullhypobaric hypoxiaapnea syndromehippocampusoxidative stressbibliometric study |
| spellingShingle | Jiexin Zhang Songyuan Tang Chao Chen Hezhong Jiang Hai Liao Huawei Liu Li Wang Xin Chen A bibliometric analysis of the studies in high-altitude induced sleep disturbances and cognitive impairment research Frontiers in Physiology hypobaric hypoxia apnea syndrome hippocampus oxidative stress bibliometric study |
| title | A bibliometric analysis of the studies in high-altitude induced sleep disturbances and cognitive impairment research |
| title_full | A bibliometric analysis of the studies in high-altitude induced sleep disturbances and cognitive impairment research |
| title_fullStr | A bibliometric analysis of the studies in high-altitude induced sleep disturbances and cognitive impairment research |
| title_full_unstemmed | A bibliometric analysis of the studies in high-altitude induced sleep disturbances and cognitive impairment research |
| title_short | A bibliometric analysis of the studies in high-altitude induced sleep disturbances and cognitive impairment research |
| title_sort | bibliometric analysis of the studies in high altitude induced sleep disturbances and cognitive impairment research |
| topic | hypobaric hypoxia apnea syndrome hippocampus oxidative stress bibliometric study |
| url | https://www.frontiersin.org/articles/10.3389/fphys.2023.1133059/full |
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