Menstrual blood-derived mesenchymal stromal cells: impact of preconditioning on the cargo of extracellular vesicles as potential therapeutics

Abstract Background Mesenchymal stromal cells (MSCs) have been shown to exert their therapeutic effects through the secretion of broad spectrum of paracrine factors, including extracellular vesicles (EVs). Accordingly, EVs are being pursued as a promising alternative to cell-based therapies. Menstru...

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Main Authors: María Ángeles de Pedro, Esther López, Francisco Manuel González-Nuño, María Pulido, Verónica Álvarez, Ana María Marchena, Christian Preußer, Witold Szymański, Elke Pogge von Strandmann, Johannes Graumann, Francisco Miguel Sánchez-Margallo, Javier G. Casado, María Gómez-Serrano
Format: Article
Jezik:English
Izdano: BMC 2023-07-01
Serija:Stem Cell Research & Therapy
Teme:
Online dostop:https://doi.org/10.1186/s13287-023-03413-5